Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains

AgNPs are employed in several applications, and we used Ipomoea carnea aqueous leaves extract to enhance the metal nanoparticle synthesis process. This study suggested that aqueous extract from I. carnea leaves can reduce silver nitrate (AgNO3) and act as a stabilizing and capping agent. The specifi...

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Main Authors: Ramveer Singh, Narashans Alok Sagar, Navneet Kumar
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417422000383
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author Ramveer Singh
Narashans Alok Sagar
Navneet Kumar
author_facet Ramveer Singh
Narashans Alok Sagar
Navneet Kumar
author_sort Ramveer Singh
collection DOAJ
description AgNPs are employed in several applications, and we used Ipomoea carnea aqueous leaves extract to enhance the metal nanoparticle synthesis process. This study suggested that aqueous extract from I. carnea leaves can reduce silver nitrate (AgNO3) and act as a stabilizing and capping agent. The specific Plasmon resonance (SPR) was found between 390-410 ​nm in a UV–Vis spectrophotometer. Field Emission Scanning Electron Microscope (FE-SEM) and X-ray diffraction (XRD) analysis confirm the size between 11.21-46.90 ​nm with spherical face-center-cubic (FCC) crystals. Additionally, the antibacterial activity of synthesized AgNPs was also evaluated against four standard bacterial pathogens i.e. Klebsiella pneumoniae (MTCC 432), Staphylococcus aureus (MTCC 1144), Streptococcus pneumoniae (MTCC 655), and Pseudomonas aeruginosa (MTCC 2474) and Brine shrimp lethality assay (BSLA) was used to check the toxicity. Synthesized AgNPs were found significantly effective against all MTCC strains with a 1359.03 ​ng/mL LC50 value.
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spelling doaj.art-3bea2681c3014e01a47cc948f506c3ce2022-12-22T04:23:12ZengElsevierEuropean Journal of Medicinal Chemistry Reports2772-41742022-12-016100066Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strainsRamveer Singh0Narashans Alok Sagar1Navneet Kumar2Department of Botany and Microbiology, Gurukula Kangri (Deemed to be University), Haridwar, India; Livestock Products Technology Division, Indian Veterinary Research Institute, Izatnagar, India; Corresponding author. Department of Botany and Microbiology, Gurukula Kangri (Deemed to be University), Haridwar, India.Livestock Products Technology Division, Indian Veterinary Research Institute, Izatnagar, IndiaDepartment of Botany and Microbiology, Gurukula Kangri (Deemed to be University), Haridwar, IndiaAgNPs are employed in several applications, and we used Ipomoea carnea aqueous leaves extract to enhance the metal nanoparticle synthesis process. This study suggested that aqueous extract from I. carnea leaves can reduce silver nitrate (AgNO3) and act as a stabilizing and capping agent. The specific Plasmon resonance (SPR) was found between 390-410 ​nm in a UV–Vis spectrophotometer. Field Emission Scanning Electron Microscope (FE-SEM) and X-ray diffraction (XRD) analysis confirm the size between 11.21-46.90 ​nm with spherical face-center-cubic (FCC) crystals. Additionally, the antibacterial activity of synthesized AgNPs was also evaluated against four standard bacterial pathogens i.e. Klebsiella pneumoniae (MTCC 432), Staphylococcus aureus (MTCC 1144), Streptococcus pneumoniae (MTCC 655), and Pseudomonas aeruginosa (MTCC 2474) and Brine shrimp lethality assay (BSLA) was used to check the toxicity. Synthesized AgNPs were found significantly effective against all MTCC strains with a 1359.03 ​ng/mL LC50 value.http://www.sciencedirect.com/science/article/pii/S2772417422000383Ipomoea carneaGreen synthesisAgNPsAntimicrobialFE-SEMEDX
spellingShingle Ramveer Singh
Narashans Alok Sagar
Navneet Kumar
Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
European Journal of Medicinal Chemistry Reports
Ipomoea carnea
Green synthesis
AgNPs
Antimicrobial
FE-SEM
EDX
title Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
title_full Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
title_fullStr Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
title_full_unstemmed Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
title_short Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains
title_sort bio inspired green fabrication of silver nanoparticles agnps using aqueous leaves extract of ipomoea carnea jacq to tackle multiple drug resistance mtcc bacterial strains
topic Ipomoea carnea
Green synthesis
AgNPs
Antimicrobial
FE-SEM
EDX
url http://www.sciencedirect.com/science/article/pii/S2772417422000383
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