Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan
OBJECTIVE: To determine frequency of transmission of HIV from mother to child at Aziz Bhatti Shaheed Teaching Hospital Gujrat. METHODOLOGY: Cross-sectional study conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in Department of Gynecology and Obstetric Unit II from January 2012 to March 20...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Liaquat University of Medical and Health Sciences
2021-03-01
|
| Series: | JLUMHS |
| Subjects: |
| _version_ | 1798027387921760256 |
|---|---|
| author | Shahida Husain Tarar Muhammad Afzal Syed Muhammad Ali Shah Zamir Butt Saleem Raza Shah Mansoor Hassan |
| author_facet | Shahida Husain Tarar Muhammad Afzal Syed Muhammad Ali Shah Zamir Butt Saleem Raza Shah Mansoor Hassan |
| author_sort | Shahida Husain Tarar |
| collection | DOAJ |
| description | OBJECTIVE: To determine frequency of transmission of HIV from mother to child at Aziz Bhatti Shaheed Teaching Hospital Gujrat.
METHODOLOGY: Cross-sectional study conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in Department of Gynecology and Obstetric Unit II from January 2012 to March 2019 using non-probability consecutive sampling. Patients who tested positive for HIV and reached full term were included. Mothers were started ART at time of diagnosis. Infant prophylaxis was done according to WHO guidelines. Counseling regarding breastfeeding was done. HIV status of infants was noted at 12 weeks after birth. A total of 51 patients were included. SPSS 20.0 was used for data analysis.
RESULTS: Fifty-one patients included having mean age 29.45+3.15 years. All patients were diagnosed during pregnancy. ART was initiated in 17(33.3%) in first trimester, 10(19.6%) in second trimester, 20(39.2%) in third trimester and in 4(7.8%) post-partum. At 6 weeks follow up of mothers, 46(90.2%) were stable, 3(5.9%) lost to follow up and 2(3.9%) mothers died post-partum at home. At 12 weeks follow up of infants 39(76.5%) tested negative for HIV, 2(3.9%) were tested positive, 7(13.7%) lost to follow up and 3(5.9%) infants died during this period. In alive and tested infants 2 out of 41 were tested positive, making HIV transmission to children from mothers to be 4.9%.
CONCLUSION: HIV transmission to children form mothers is high in our population and there is need for active screening of all pregnant mothers. |
| first_indexed | 2024-04-11T18:51:35Z |
| format | Article |
| id | doaj.art-3beac931a5fb4daa95f44a51132e1c70 |
| institution | Directory Open Access Journal |
| issn | 1729-0341 2309-8627 |
| language | English |
| last_indexed | 2024-04-11T18:51:35Z |
| publishDate | 2021-03-01 |
| publisher | Liaquat University of Medical and Health Sciences |
| record_format | Article |
| series | JLUMHS |
| spelling | doaj.art-3beac931a5fb4daa95f44a51132e1c702022-12-22T04:08:21ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272021-03-01201121610.22442/jlumhs.2021.00792Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in PakistanShahida Husain Tarar 0Muhammad Afzal 1Syed Muhammad Ali Shah 2Zamir Butt 3Saleem Raza Shah 4Mansoor Hassan 5Associate Professor Department of Gynecology and Obstetrics Nawaz Sharif Medical College Gujrat, Punjab-Pakistan.Associate Professor Department of Medicine Nawaz Sharif Medical College Gujrat, Punjab-Pakistan.Consultant Physician Aziz Bhatti Shaheed Teaching Hospital Gujrat, Punjab-Pakistan.Assistant Professor Department of Medicine Nawaz Sharif Medical College Gujrat, Punjab-Pakistan.Senior Registrar Department of Surgery Nawaz Sharif Medical College Gujrat, Punjab-Pakistan.Associate Professor Department of Medicine Sialkot Medical College Sialkot, Punjab-Pakistan.OBJECTIVE: To determine frequency of transmission of HIV from mother to child at Aziz Bhatti Shaheed Teaching Hospital Gujrat. METHODOLOGY: Cross-sectional study conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in Department of Gynecology and Obstetric Unit II from January 2012 to March 2019 using non-probability consecutive sampling. Patients who tested positive for HIV and reached full term were included. Mothers were started ART at time of diagnosis. Infant prophylaxis was done according to WHO guidelines. Counseling regarding breastfeeding was done. HIV status of infants was noted at 12 weeks after birth. A total of 51 patients were included. SPSS 20.0 was used for data analysis. RESULTS: Fifty-one patients included having mean age 29.45+3.15 years. All patients were diagnosed during pregnancy. ART was initiated in 17(33.3%) in first trimester, 10(19.6%) in second trimester, 20(39.2%) in third trimester and in 4(7.8%) post-partum. At 6 weeks follow up of mothers, 46(90.2%) were stable, 3(5.9%) lost to follow up and 2(3.9%) mothers died post-partum at home. At 12 weeks follow up of infants 39(76.5%) tested negative for HIV, 2(3.9%) were tested positive, 7(13.7%) lost to follow up and 3(5.9%) infants died during this period. In alive and tested infants 2 out of 41 were tested positive, making HIV transmission to children from mothers to be 4.9%. CONCLUSION: HIV transmission to children form mothers is high in our population and there is need for active screening of all pregnant mothers.mother to child hiv transmissionhivhiv in infantspregnancy |
| spellingShingle | Shahida Husain Tarar Muhammad Afzal Syed Muhammad Ali Shah Zamir Butt Saleem Raza Shah Mansoor Hassan Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan JLUMHS mother to child hiv transmission hiv hiv in infants pregnancy |
| title | Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan |
| title_full | Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan |
| title_fullStr | Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan |
| title_full_unstemmed | Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan |
| title_short | Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan |
| title_sort | maternal transmission of human immunodeficiency virus to infants in a tertiary care hospital in pakistan |
| topic | mother to child hiv transmission hiv hiv in infants pregnancy |
| work_keys_str_mv | AT shahidahusaintarar maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan AT muhammadafzal maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan AT syedmuhammadalishah maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan AT zamirbutt maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan AT saleemrazashah maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan AT mansoorhassan maternaltransmissionofhumanimmunodeficiencyvirustoinfantsinatertiarycarehospitalinpakistan |