Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate

Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate

Abstract Background Extracellular vesicles (EVs) are important in the intercellular communication of the central nervous system, and their release is increased during neuroinflammation. Our previous data demonstrated an increased release of EVs during HIV-1 infection and immune activation in glial c...

Full description

Bibliographic Details
Main Authors: Beiqing Wu, Jianhui Liu, Runze Zhao, Yuju Li, Justin Peer, Alexander L. Braun, Lixia Zhao, Yi Wang, Zenghan Tong, Yunlong Huang, Jialin C. Zheng
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Neuroinflammation
Subjects:
Glutamine metabolism
α-Ketoglutarate
Extracellular vesicles
HIV-1
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1120-x

Internet

http://link.springer.com/article/10.1186/s12974-018-1120-x

Similar Items