Impact of Breast Cancer and Germline BRCA Pathogenic Variants on Fertility Preservation in Young Women

Impact of Breast Cancer and Germline BRCA Pathogenic Variants on Fertility Preservation in Young Women

Background: Several studies have suggested that breast cancer (BC) and germline BRCA pathogenic variants (gBRCA PVs) could have a deleterious impact on ovarian reserve. Nevertheless, data are limited and mixed. Our objective was to evaluate the performance of fertility preservation (FP) in terms of...

Full description

Bibliographic Details
Main Authors:	Elze Prokurotaite, Margherita Condorelli, Julie Dechene, Jason Bouziotis, Matteo Lambertini, Isabelle Demeestere
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Life
Subjects:	fertility preservation oocyte cryopreservation ovarian reserve BRCA mutation germline BRCA pathogenic variants breast cancer
Online Access:	https://www.mdpi.com/2075-1729/13/4/930

Similar Items

Reproductive issues in carriers of germline pathogenic variants in the BRCA1/2 genes: an expert meeting
by: Barbara Buonomo, et al.
Published: (2021-09-01)

Prevalence of BRCA1 and BRCA2 germline variants in an unselected pancreatic cancer patient cohort in Pakistan
by: Noor Muhammad, et al.
Published: (2023-11-01)

Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
by: Yomali Ferreyra, et al.
Published: (2023-08-01)

Analysis of BRCA Germline Mutations in Chinese Prostate Cancer Patients
by: Wei Chen, et al.
Published: (2022-02-01)

Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia
by: Dorra Ben Ayed-Guerfali, et al.
Published: (2021-03-01)

Assessing frequency and clinical outcomes of BRCA mutated ovarian cancer in Saudi women
by: Naela Agha, et al.
Published: (2022-01-01)

Prevalence and clinical implications of germline mutations among Jordanian patients with ovarian cancer. The Jordanian exploratory cancer genetics (Jo‐ECAG) ovarian study
by: Hikmat Abdel‐Razeq, et al.
Published: (2023-04-01)

BRCA-associated hereditary male cancers: can gender affect the prevalence and spectrum of germline pathogenic variants?
by: Daniele Fanale, et al.
Published: (2024-06-01)

Limited Independent Follow-Up with Germline Testing of Variants Detected in BRCA1 and BRCA2 by Tumor-Only Sequencing
by: Carol J. Nowlen, et al.
Published: (2024-02-01)

Germline mutations in BRCA1 and BRCA2 among Brazilian women with ovarian cancer treated in the Public Health System
by: Caroline de Oliveira Ferreira, et al.
Published: (2024-04-01)

Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil
by: Deborah Porto Cotrim, et al.
Published: (2019-01-01)

Characteristics of BRCA1/2 pathogenic germline mutations in chinese NSCLC patients and a comparison with HBOC
by: Zheyuan Xu, et al.
Published: (2021-02-01)

Fertility Preservation in BRCA1/2 Germline Mutation Carriers: An Overview
by: Erica Silvestris, et al.
Published: (2024-05-01)

Germline BRCA, chemotherapy response scores, and survival in the neoadjuvant treatment of ovarian cancer
by: Yong Jae Lee, et al.
Published: (2020-03-01)

Pathogenic germline variants in BRCA1 and TP53 increase lung cancer risk in Chinese
by: Bing Wei, et al.
Published: (2023-12-01)

Clinical application of artificial neural network (ANN) modeling to predict BRCA1/2 germline deleterious variants in Chinese bilateral primary breast cancer patients
by: Yan Li, et al.
Published: (2022-11-01)

Tumor Testing for Somatic and Germline BRCA1/BRCA2 Variants in Ovarian Cancer Patients in the Context of Strong Founder Effects
by: Ana Peixoto, et al.
Published: (2020-07-01)

Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study
by: Laurie Denis-Laroque, et al.
Published: (2021-10-01)

Is Breast Conserving Surgery Efficacious in Breast Cancer Patients with BRCA1 or BRCA2 Germline Mutation?
by: Emiroglu S, et al.
Published: (2023-02-01)

The Features of BRCA1 and BRCA2 Germline Mutations in Hakka Ovarian Cancer Patients: BRCA1 C.536 A>T Maybe a Founder Mutation in This Population
by: Luo Y, et al.
Published: (2022-03-01)

Prevalence and clinical significance of pathogenic germline <i>BRCA1</i>/<i>2</i> mutations in Chinese non-small cell lung cancer patients
by: Xingsheng Hu, et al.
Published: (2019-09-01)

Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome
by: Ashour M, et al.
Published: (2019-07-01)

Association Between Germline BRCA1/2 Gene Variants and Clinicopathological Features of Ovarian Cancer
by: Luo Y, et al.
Published: (2024-01-01)

Overview on population screening for carriers with germline BRCA mutation in China
by: Huijun Lei, et al.
Published: (2022-11-01)

Primary Peritoneal Carcinosarcoma in a Breast Cancer Patient Harboring a Germline BRCA2 Pathogenic Variant: Case Report
by: Luciana Beatriz Mendes Gomes, et al.
Published: (2024-01-01)

Los olvidados: Non-BRCA variants associated with Hereditary breast cancer in Mexican population
by: Dione Aguilar, et al.
Published: (2025-01-01)

Prevalence and Spectrum of Germline BRCA1 and BRCA2 Variants of Uncertain Significance in Breast/Ovarian Cancer: Mysterious Signals From the Genome
by: Daniele Fanale, et al.
Published: (2021-06-01)

Germline variants profiling of BRCA1 and BRCA2 in Chinese Hakka breast and ovarian cancer patients
by: Yunuo Zhang, et al.
Published: (2022-08-01)

Erratum: Prevalence and Spectrum of Germline BRCA1 and BRCA2 Variants of Uncertain Significance in Breast/Ovarian Cancer: Mysterious Signals From the Genome
by: Frontiers Production Office
Published: (2022-05-01)

Prostate Cancer: Germline Mutations in BRCA1 and BRCA2
by: Pankaja Umarane, et al.
Published: (2023-03-01)

Characteristics of breast cancer in BRCA1/BRCA2 mutation carriers and non-carriersfrom a genetic counseling unit in Croatia
by: Snježana Ramić, et al.
Published: (2020-01-01)

<i>BRCA1/2</i> Mutation Types Do Not Affect Prognosis in Ovarian Cancer Patients
by: Michalis Liontos, et al.
Published: (2021-11-01)

Prognostic significance of germline BRCA mutations in patients with HER2-POSITIVE breast cancer
by: A. Viansone, et al.
Published: (2022-10-01)

Expert consensus on population-based BRCA germline mutation screening in China (2024 edition)
by: China Anti-Cancer Association Tumor Biomarker Professional Committee, Shanghai Anti-Cancer Association Tumor Biomarker Professional Committee
Published: (2024-02-01)

Association of BRCA Mutations and Anti-müllerian Hormone Level in Young Breast Cancer Patients
by: Kyung-A Son, et al.
Published: (2019-04-01)

Serum testosterone and prostate cancer in men with germline BRCA1/2 pathogenic variants
by: Alexander Dias, et al.
Published: (2023-05-01)

BRCA1 and BRCA2 and Inherited Predisposition to Breast and Ovarian Cancers
by: Patricia N. Tonin
Published: (2002-12-01)

Elective Oocyte Cryopreservation
by: Saeideh Dashti, et al.
Published: (2025-02-01)

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations
by: Robert L. Hollis, et al.
Published: (2018-01-01)

Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples
by: Falk Zakrzewski, et al.
Published: (2019-04-01)