Age-related blood antioxidant capacity in men and women
The aim of the study was to assess the blood antioxidant capacity in men and women in relation to age. The subjects were 19 men (YM) and 19 women (YW) aged 25-32 years, and 11 men (OM) and 11 women (OW) aged 63-71 years, all sedentary. The following factors were determined: the activity of erythrocy...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Society of Medical Biochemists of Serbia, Belgrade
2011-01-01
|
| Series: | Journal of Medical Biochemistry |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2011/1452-82581102103H.pdf |
| _version_ | 1818434375904133120 |
|---|---|
| author | Hübner-Wozniak Elzbieta Okecka-Szymanska Joanna Stupnicki Romuald Malara Marzena Kozdron Ewa |
| author_facet | Hübner-Wozniak Elzbieta Okecka-Szymanska Joanna Stupnicki Romuald Malara Marzena Kozdron Ewa |
| author_sort | Hübner-Wozniak Elzbieta |
| collection | DOAJ |
| description | The aim of the study was to assess the blood antioxidant capacity in men and women in relation to age. The subjects were 19 men (YM) and 19 women (YW) aged 25-32 years, and 11 men (OM) and 11 women (OW) aged 63-71 years, all sedentary. The following factors were determined: the activity of erythrocyte superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPX), catalase (CAT), total antioxidant status (TAS), as well as plasma retinol, a-tocopherol, uric acid and total protein concentrations. The sum of standardized activities of antioxidant enzymes was calculated to compare agerelated changes in the total capacity of the erythrocyte antioxidant defense. No significant age-related changes in SOD activity were observed; mean CAT activity was higher in older women and men than in younger subjects. Mean activity of GPX was higher and that of GR lower in older subjects compared to the younger ones. The calculated total erythrocyte antioxidant enzyme capacity in younger and older subjects rendered similar values. No significant differences in plasma retinol and a-tocopherol concentrations in relation to sex or age were noted. The plasma total protein level was significantly lower in younger women and men compared to their older mates. It was concluded that the total erythrocyte enzymatic antioxidant capacity did not change with age. The results obtained clearly show that multiple factors may contribute to the ageing process. . |
| first_indexed | 2024-12-14T16:36:00Z |
| format | Article |
| id | doaj.art-3bf9d90d3c62463ea056b840fa300729 |
| institution | Directory Open Access Journal |
| issn | 1452-8258 1452-8266 |
| language | English |
| last_indexed | 2024-12-14T16:36:00Z |
| publishDate | 2011-01-01 |
| publisher | Society of Medical Biochemists of Serbia, Belgrade |
| record_format | Article |
| series | Journal of Medical Biochemistry |
| spelling | doaj.art-3bf9d90d3c62463ea056b840fa3007292022-12-21T22:54:28ZengSociety of Medical Biochemists of Serbia, BelgradeJournal of Medical Biochemistry1452-82581452-82662011-01-013021031081452-82581102103HAge-related blood antioxidant capacity in men and womenHübner-Wozniak Elzbieta0Okecka-Szymanska Joanna1Stupnicki Romuald2Malara Marzena3Kozdron Ewa4Department of Biochemistry, University of Physical Education, Warsaw, PolandDepartment of Biochemistry, University of Physical Education, Warsaw, PolandDepartment of Statistics and Computer Science, University of Physical Education, Warsaw, PolandDepartment of Biochemistry, University of Physical Education, Warsaw, PolandDepartment of Theory and Methodology of Recreation, University of Physical Education, Warsaw, PolandThe aim of the study was to assess the blood antioxidant capacity in men and women in relation to age. The subjects were 19 men (YM) and 19 women (YW) aged 25-32 years, and 11 men (OM) and 11 women (OW) aged 63-71 years, all sedentary. The following factors were determined: the activity of erythrocyte superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPX), catalase (CAT), total antioxidant status (TAS), as well as plasma retinol, a-tocopherol, uric acid and total protein concentrations. The sum of standardized activities of antioxidant enzymes was calculated to compare agerelated changes in the total capacity of the erythrocyte antioxidant defense. No significant age-related changes in SOD activity were observed; mean CAT activity was higher in older women and men than in younger subjects. Mean activity of GPX was higher and that of GR lower in older subjects compared to the younger ones. The calculated total erythrocyte antioxidant enzyme capacity in younger and older subjects rendered similar values. No significant differences in plasma retinol and a-tocopherol concentrations in relation to sex or age were noted. The plasma total protein level was significantly lower in younger women and men compared to their older mates. It was concluded that the total erythrocyte enzymatic antioxidant capacity did not change with age. The results obtained clearly show that multiple factors may contribute to the ageing process. .https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2011/1452-82581102103H.pdfantioxidant enzymesnon-enzymatic antioxidantsmenwomenageing |
| spellingShingle | Hübner-Wozniak Elzbieta Okecka-Szymanska Joanna Stupnicki Romuald Malara Marzena Kozdron Ewa Age-related blood antioxidant capacity in men and women Journal of Medical Biochemistry antioxidant enzymes non-enzymatic antioxidants men women ageing |
| title | Age-related blood antioxidant capacity in men and women |
| title_full | Age-related blood antioxidant capacity in men and women |
| title_fullStr | Age-related blood antioxidant capacity in men and women |
| title_full_unstemmed | Age-related blood antioxidant capacity in men and women |
| title_short | Age-related blood antioxidant capacity in men and women |
| title_sort | age related blood antioxidant capacity in men and women |
| topic | antioxidant enzymes non-enzymatic antioxidants men women ageing |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2011/1452-82581102103H.pdf |
| work_keys_str_mv | AT hubnerwozniakelzbieta agerelatedbloodantioxidantcapacityinmenandwomen AT okeckaszymanskajoanna agerelatedbloodantioxidantcapacityinmenandwomen AT stupnickiromuald agerelatedbloodantioxidantcapacityinmenandwomen AT malaramarzena agerelatedbloodantioxidantcapacityinmenandwomen AT kozdronewa agerelatedbloodantioxidantcapacityinmenandwomen |