The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification

The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification

AbstractContext Huangqi Guizhi Wuwu Decoction (HGWD) is effective in treating ischaemic stroke (IS). However, its mechanism of action is still unclear.Objective Network pharmacology integrated with in vivo experiments were used to clarify the underlying mechanisms of HGWD for treating IS.Materials a...

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Bibliographic Details
Main Authors: Weiguo Liao, Minchun Wang, Ying Wu, Jinyan Du, Yaxin Li, Anyu Su, Lanying Zhong, Zi Xie, Mingyu Gong, Junhui Liang, Pengcheng Wang, Zai Liu, Lisheng Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Chinese medicine formula
molecular docking
PI3K-Akt pathway
HIF-1 pathways
inflammation
apoptosis
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2023.2230477

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