<i>Leishmania</i> Infection-Induced Proteolytic Processing of SIRPα in Macrophages

<i>Leishmania</i> Infection-Induced Proteolytic Processing of SIRPα in Macrophages

The shedding of cell surface receptors may bring synergistic outcomes through the loss of receptor-mediated cell signaling and competitive binding of the shed soluble receptor to its ligand. Thus, soluble receptors have both biological importance and diagnostic importance as biomarkers in immunologi...

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Bibliographic Details
Main Authors: Hana Hirai, Jing Hong, Wataru Fujii, Chizu Sanjoba, Yasuyuki Goto
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pathogens
Subjects:
visceral leishmaniasis
SIRPα
ectodomain shedding
ADAM
Online Access:https://www.mdpi.com/2076-0817/12/4/593

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