Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report
Squamous Cell Carcinoma (SCC) is the second most common eyelid malignancy worldwide. SCC is an aggressive tumour, with the ability to cause significant morbidity, mortality and the risk of rapid spread. Hence, urgent diagnosis and management is essential. SCC may mimic other benign and malignant l...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/10879/30621_CE(RA1)_F(AP)_PF1(VSU_GG)_PFA(MJ_GG).pdf |
| _version_ | 1811248431646113792 |
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| author | Smriti Nagpal Gupta Sushil Kumar Ruchi Goel Charu Sagar Okram Birbala |
| author_facet | Smriti Nagpal Gupta Sushil Kumar Ruchi Goel Charu Sagar Okram Birbala |
| author_sort | Smriti Nagpal Gupta |
| collection | DOAJ |
| description | Squamous Cell Carcinoma (SCC) is the second most common eyelid malignancy worldwide. SCC is an aggressive tumour, with the
ability to cause significant morbidity, mortality and the risk of rapid spread. Hence, urgent diagnosis and management is essential.
SCC may mimic other benign and malignant lesions. Its definite diagnosis is generally done by biopsy and immunohistochemistry.
Orbital invasion warrants treatment by orbital exenteration. There are chances of incomplete tumour clearance and recurrence, with
a five year survival Rate of about 60%. Herein, we describe a young male patient with a massive tumour engulfing the entire orbit,
and spilling over to the surface and periocular skin. There was a fungating, multilobulated mass of about 10 X 10 cm in size, with
areas of necrosis and secondary infection. The tumour had invaded and destroyed all the orbital structures. However, the nasal
cavity and maxillary sinus was free of tumour and there was no evidence of metastasis.
The patient underwent surgical debulking of the tumour via orbital exenteration, followed by adjuvant radiotherapy. Histopathology
revealed, well differentiated SCC. On follow up, the patient was systemically well, with no evidence of metastasis and the surgical
site appeared healthy. |
| first_indexed | 2024-04-12T15:27:54Z |
| format | Article |
| id | doaj.art-3bfc435a0d1d43dfa072ff6498c841f1 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-12T15:27:54Z |
| publishDate | 2017-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-3bfc435a0d1d43dfa072ff6498c841f12022-12-22T03:27:12ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-11-011111ND01ND0310.7860/JCDR/2017/30621.10879Massive Squamous Cell Carcinoma of the Orbit: A Rare Case ReportSmriti Nagpal Gupta0Sushil Kumar1Ruchi Goel2Charu Sagar3Okram Birbala4Senior Resident, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.Director Professor, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.Professor, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.Junior Resident, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.Junior Resident, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.Squamous Cell Carcinoma (SCC) is the second most common eyelid malignancy worldwide. SCC is an aggressive tumour, with the ability to cause significant morbidity, mortality and the risk of rapid spread. Hence, urgent diagnosis and management is essential. SCC may mimic other benign and malignant lesions. Its definite diagnosis is generally done by biopsy and immunohistochemistry. Orbital invasion warrants treatment by orbital exenteration. There are chances of incomplete tumour clearance and recurrence, with a five year survival Rate of about 60%. Herein, we describe a young male patient with a massive tumour engulfing the entire orbit, and spilling over to the surface and periocular skin. There was a fungating, multilobulated mass of about 10 X 10 cm in size, with areas of necrosis and secondary infection. The tumour had invaded and destroyed all the orbital structures. However, the nasal cavity and maxillary sinus was free of tumour and there was no evidence of metastasis. The patient underwent surgical debulking of the tumour via orbital exenteration, followed by adjuvant radiotherapy. Histopathology revealed, well differentiated SCC. On follow up, the patient was systemically well, with no evidence of metastasis and the surgical site appeared healthy.https://jcdr.net/articles/PDF/10879/30621_CE(RA1)_F(AP)_PF1(VSU_GG)_PFA(MJ_GG).pdfexenterationorbital sccsquamous cell tumour |
| spellingShingle | Smriti Nagpal Gupta Sushil Kumar Ruchi Goel Charu Sagar Okram Birbala Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report Journal of Clinical and Diagnostic Research exenteration orbital scc squamous cell tumour |
| title | Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report |
| title_full | Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report |
| title_fullStr | Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report |
| title_full_unstemmed | Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report |
| title_short | Massive Squamous Cell Carcinoma of the Orbit: A Rare Case Report |
| title_sort | massive squamous cell carcinoma of the orbit a rare case report |
| topic | exenteration orbital scc squamous cell tumour |
| url | https://jcdr.net/articles/PDF/10879/30621_CE(RA1)_F(AP)_PF1(VSU_GG)_PFA(MJ_GG).pdf |
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