Characterization of sulfated polysaccharide activity against virulent Plasmodium falciparum PHISTb/RLP1 protein [version 2; peer review: 2 approved]

Characterization of sulfated polysaccharide activity against virulent Plasmodium falciparum PHISTb/RLP1 protein [version 2; peer review: 2 approved]

Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving targeted drug discovery is less cumbersome and th...

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Bibliographic Details
Main Authors: Dennis W. Juma, Benjamin H. Opot, Hosea M. Akala, Amanda L. Roth, Ben M. Andagalu, Jennifer M. Mutisya, Johnson K. Kinyua, Victor A. Mobegi, Raphael O. Okoth, Martha N. Kivecu, Edwin W. Mwakio, Gladys C. Chemwor, Redempta A. Yeda, Agnes C. Cheruiyot, Jackline A. Juma, Charles O. Okello
Format: Article
Language:English
Published: F1000 Research Ltd 2022-04-01
Series:F1000Research
Subjects:
Exported proteins
Sulfated polysaccharides
PHISTb/RLP1
Interactions
P. falciparum
Anti-malarials
eng
Online Access:https://f1000research.com/articles/9-1268/v2

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