Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults
Purpose We aimed to assess if lipid accumulation product (LAP) could outperform body mass index (BMI) as a marker for diabetes diagnosis. Methods We analyzed the results of a national physical examination project in Urumqi, China. This project was conducted in 442 community clinics in Urumqi from Oc...
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PeerJ Inc.
2020-02-01
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| Online Access: | https://peerj.com/articles/8483.pdf |
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| author | Tian Tian Hualian Pei Zhen Chen Gulisiya Hailili Shuxia Wang Yong Sun Hua Yao Dai Jianghong |
| author_facet | Tian Tian Hualian Pei Zhen Chen Gulisiya Hailili Shuxia Wang Yong Sun Hua Yao Dai Jianghong |
| author_sort | Tian Tian |
| collection | DOAJ |
| description | Purpose We aimed to assess if lipid accumulation product (LAP) could outperform body mass index (BMI) as a marker for diabetes diagnosis. Methods We analyzed the results of a national physical examination project in Urumqi, China. This project was conducted in 442 community clinics in Urumqi from October 2016 to February 2017. Results LAP was highly correlated with diabetes. The subjects with higher amounts of LAP had a higher risk of diabetes, and the prevalence of diabetes in the fourth quartile of LAP was dramatically higher than in the first quartile (5.72% vs. 21.76%). The adjusted odds ratios (AOR) associated with diabetes in the fourth quartile of LAP was significantly higher than the AOR associated with diabetes in the first quartile, and when BMI ≥ 28 kg/m2 was compared with BMI < 28 kg/m2 (3.24 (3.11, 3.37) vs. 1.65 (1.60, 1.70)). The LAP’s area under the curve (AUC) was significantly higher than the BMI’s AUC when based on diabetes (0.655 vs. 0.604). In the normal BMI group, 34% of participants had a LAP value higher than the cutoff point found during ROC analysis. In this subgroup, we observed a significantly higher prevalence of diabetes that was similar to that of the subgroup with a BMI ≥ 28 kg/m2, and both of their LAP values were higher than the cutoff point. Conclusion When use as a tool for diabetes diagnosis, LAP performed better than BMI, implying that LAP could be a preferable anthropometry assessment. |
| first_indexed | 2024-03-09T08:04:16Z |
| format | Article |
| id | doaj.art-3bff5bdd7e50455680a74d182d512afb |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T08:04:16Z |
| publishDate | 2020-02-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-3bff5bdd7e50455680a74d182d512afb2023-12-03T00:25:20ZengPeerJ Inc.PeerJ2167-83592020-02-018e848310.7717/peerj.8483Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adultsTian Tian0Hualian Pei1Zhen Chen2Gulisiya Hailili3Shuxia Wang4Yong Sun5Hua Yao6Dai Jianghong7School of Public Health, Xinjiang Medical University, Urumqi, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, ChinaSchool of Health Management, Xinjiang Medical University, Urumqi, ChinaSchool of Health Management, Xinjiang Medical University, Urumqi, ChinaSchool of Health Management, Xinjiang Medical University, Urumqi, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, ChinaPurpose We aimed to assess if lipid accumulation product (LAP) could outperform body mass index (BMI) as a marker for diabetes diagnosis. Methods We analyzed the results of a national physical examination project in Urumqi, China. This project was conducted in 442 community clinics in Urumqi from October 2016 to February 2017. Results LAP was highly correlated with diabetes. The subjects with higher amounts of LAP had a higher risk of diabetes, and the prevalence of diabetes in the fourth quartile of LAP was dramatically higher than in the first quartile (5.72% vs. 21.76%). The adjusted odds ratios (AOR) associated with diabetes in the fourth quartile of LAP was significantly higher than the AOR associated with diabetes in the first quartile, and when BMI ≥ 28 kg/m2 was compared with BMI < 28 kg/m2 (3.24 (3.11, 3.37) vs. 1.65 (1.60, 1.70)). The LAP’s area under the curve (AUC) was significantly higher than the BMI’s AUC when based on diabetes (0.655 vs. 0.604). In the normal BMI group, 34% of participants had a LAP value higher than the cutoff point found during ROC analysis. In this subgroup, we observed a significantly higher prevalence of diabetes that was similar to that of the subgroup with a BMI ≥ 28 kg/m2, and both of their LAP values were higher than the cutoff point. Conclusion When use as a tool for diabetes diagnosis, LAP performed better than BMI, implying that LAP could be a preferable anthropometry assessment.https://peerj.com/articles/8483.pdfType 2 diabetesBody mass indexLipid accumulation product |
| spellingShingle | Tian Tian Hualian Pei Zhen Chen Gulisiya Hailili Shuxia Wang Yong Sun Hua Yao Dai Jianghong Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults PeerJ Type 2 diabetes Body mass index Lipid accumulation product |
| title | Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults |
| title_full | Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults |
| title_fullStr | Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults |
| title_full_unstemmed | Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults |
| title_short | Comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215,651 Chinese adults |
| title_sort | comparison of lipid accumulation product and body mass index as indicators of diabetes diagnosis among 215 651 chinese adults |
| topic | Type 2 diabetes Body mass index Lipid accumulation product |
| url | https://peerj.com/articles/8483.pdf |
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