Roles of Protein Disulfide Isomerase in Breast Cancer

Roles of Protein Disulfide Isomerase in Breast Cancer

Protein disulfide isomerase (PDI) is the endoplasmic reticulum (ER)’s most abundant and essential enzyme and serves as the primary catalyst for protein folding. Due to its apparent role in supporting the rapid proliferation of cancer cells, the selective blockade of PDI results in apoptosis through...

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Bibliographic Details
Main Authors:	Suhui Yang, Chanel Jackson, Eduard Karapetyan, Pranabananda Dutta, Dulcie Kermah, Yong Wu, Yanyuan Wu, John Schloss, Jaydutt V. Vadgama
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Cancers
Subjects:	breast cancer triple-negative breast cancer protein disulfide isomerase protein disulfide isomerase inhibitor
Online Access:	https://www.mdpi.com/2072-6694/14/3/745

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