Oral Immunization of Chickens with Probiotic <em>Lactobacillus crispatus</em> Constitutively Expressing the α-β2-ε-β1 Toxoids to Induce Protective Immunity

Oral Immunization of Chickens with Probiotic <em>Lactobacillus crispatus</em> Constitutively Expressing the α-β2-ε-β1 Toxoids to Induce Protective Immunity

<i>Clostridium perfringens</i> (<i>C. perfringens</i>) is a bacterium that commonly causes zoonotic disease. The pathogenicity of <i>C. perfringens</i> is a result of the combined action of α, β, and ε exotoxins. In this study, <i>Lactobacillus crispatus<...

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Bibliographic Details
Main Authors: Mohammad Zeb Khan, Fengsai Li, Xuewei Huang, Muhammad Nouman, Roshna Bibi, Xiaolong Fan, Han Zhou, Zhifu Shan, Li Wang, Yanping Jiang, Wen Cui, Xinyuan Qiao, Yijing Li, Xiaona Wang, Lijie Tang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Vaccines
Subjects:
<i>Lactobacillus crispatus</i>
<i>Clostridium perfringens</i>
α-β2-ε-β1 toxoid
oral immunization
protective effect
Online Access:https://www.mdpi.com/2076-393X/10/5/698

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