Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations
Purpose: We retrospectively study twenty-nine surgical cases of aggressive vertebral hemangiomas (AVHs) with neurological deficits and extradural compression to determine the optimal surgical treatment strategy for AVHs at a single institution. Methods: Patients with AVHs with neurological deficits...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Journal of Bone Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137423000489 |
| _version_ | 1797390471891255296 |
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| author | Mohamed Diaty Diarra Zengjie Zhang Zhan Wang Eloy Yinwang Hengyuan Li Shengdong Wang Peng Lin Xin Huang Zhaoming Ye |
| author_facet | Mohamed Diaty Diarra Zengjie Zhang Zhan Wang Eloy Yinwang Hengyuan Li Shengdong Wang Peng Lin Xin Huang Zhaoming Ye |
| author_sort | Mohamed Diaty Diarra |
| collection | DOAJ |
| description | Purpose: We retrospectively study twenty-nine surgical cases of aggressive vertebral hemangiomas (AVHs) with neurological deficits and extradural compression to determine the optimal surgical treatment strategy for AVHs at a single institution. Methods: Patients with AVHs with neurological deficits who underwent partial tumor resection plus decompression with or without vertebroplasty (VP), and radiotherapy between 2010 and 2021 were included in this study. Clinical characteristics, surgical outcomes, and follow-up data of the patients were reviewed retrospectively. Results: Twenty-nine AVH cases with neurological deficits and spinal instability were included in this study and treated surgically. The mean operation time of patients with decompression surgery plus VP (Groupe A) was 215.9 (120-265 min), shorter than that of decompression surgery without VP (Group B) 240.2 (120-320 min). Intraoperative blood loss was 273.3 (100–550 mL) in group A and 635.3 (200–1600 mL) in group B. In addition, a significant reduction in blood loss was observed in group A compared to the group B (p=0.0001). All patients experienced immediate pain relief and improvement in their neurological symptoms. Neurological function was assessed by the Frankel score, ASIA score, and the visual analogue scale (VAS) pain score decreased from 7.4 (4-9) to 1.3 (0-3). Of twenty-nine patients in this study, only 7% (2/29 patients) showed signs of recurrence. Conclusion: Decompression plus VP achieve good tumor control and decrease surgical complication. Preoperative vascular embolization and VP can reduce intraoperative bleeding in the treatment of AVH surgery. Moreover, postoperative radiotherapy seems to be a good technique to prevent tumor recurrence. |
| first_indexed | 2024-03-08T23:12:20Z |
| format | Article |
| id | doaj.art-3c06f71a0fdd49309c90b032a2ce24c1 |
| institution | Directory Open Access Journal |
| issn | 2212-1374 |
| language | English |
| last_indexed | 2024-03-08T23:12:20Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Bone Oncology |
| spelling | doaj.art-3c06f71a0fdd49309c90b032a2ce24c12023-12-15T07:23:59ZengElsevierJournal of Bone Oncology2212-13742023-12-0143100515Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendationsMohamed Diaty Diarra0Zengjie Zhang1Zhan Wang2Eloy Yinwang3Hengyuan Li4Shengdong Wang5Peng Lin6Xin Huang7Zhaoming Ye8Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, China; Corresponding authors at: Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Orthopedics Research Institute of Zhejiang University, Hangzhou 310000, China; Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou 310000, China; Corresponding authors at: Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.Purpose: We retrospectively study twenty-nine surgical cases of aggressive vertebral hemangiomas (AVHs) with neurological deficits and extradural compression to determine the optimal surgical treatment strategy for AVHs at a single institution. Methods: Patients with AVHs with neurological deficits who underwent partial tumor resection plus decompression with or without vertebroplasty (VP), and radiotherapy between 2010 and 2021 were included in this study. Clinical characteristics, surgical outcomes, and follow-up data of the patients were reviewed retrospectively. Results: Twenty-nine AVH cases with neurological deficits and spinal instability were included in this study and treated surgically. The mean operation time of patients with decompression surgery plus VP (Groupe A) was 215.9 (120-265 min), shorter than that of decompression surgery without VP (Group B) 240.2 (120-320 min). Intraoperative blood loss was 273.3 (100–550 mL) in group A and 635.3 (200–1600 mL) in group B. In addition, a significant reduction in blood loss was observed in group A compared to the group B (p=0.0001). All patients experienced immediate pain relief and improvement in their neurological symptoms. Neurological function was assessed by the Frankel score, ASIA score, and the visual analogue scale (VAS) pain score decreased from 7.4 (4-9) to 1.3 (0-3). Of twenty-nine patients in this study, only 7% (2/29 patients) showed signs of recurrence. Conclusion: Decompression plus VP achieve good tumor control and decrease surgical complication. Preoperative vascular embolization and VP can reduce intraoperative bleeding in the treatment of AVH surgery. Moreover, postoperative radiotherapy seems to be a good technique to prevent tumor recurrence.http://www.sciencedirect.com/science/article/pii/S2212137423000489Aggressive vertebral hemangiomasVertebroplastyDecompressionSpinal tumourRadiation therapy |
| spellingShingle | Mohamed Diaty Diarra Zengjie Zhang Zhan Wang Eloy Yinwang Hengyuan Li Shengdong Wang Peng Lin Xin Huang Zhaoming Ye Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations Journal of Bone Oncology Aggressive vertebral hemangiomas Vertebroplasty Decompression Spinal tumour Radiation therapy |
| title | Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations |
| title_full | Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations |
| title_fullStr | Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations |
| title_full_unstemmed | Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations |
| title_short | Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations |
| title_sort | surgical options for aggressive vertebral hemangiomas a case series literature review and treatment recommendations |
| topic | Aggressive vertebral hemangiomas Vertebroplasty Decompression Spinal tumour Radiation therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2212137423000489 |
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