Novel Perylene-Based Antimicrobial PDI Chromophores
The main goal of the study was to monitor the Antimicrobial activity of two novel perylene diimides which were synthesized and characterized. Antimicrobial activity was investigated against Four Mycobacterium tuberculosis strains (MT) (Mt-H37Rv, Mt-H37Ra and two clinical isolates) and two Staphyloco...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Turkish Chemical Society
2023-08-01
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| Series: | Journal of the Turkish Chemical Society, Section A: Chemistry |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/pub/jotcsa/issue/78393/1292068 |
| _version_ | 1797689182216257536 |
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| author | Cansu YILMAZ Pınar GÜNER Tülin AŞKUN Funda YÜKRÜK |
| author_facet | Cansu YILMAZ Pınar GÜNER Tülin AŞKUN Funda YÜKRÜK |
| author_sort | Cansu YILMAZ |
| collection | DOAJ |
| description | The main goal of the study was to monitor the Antimicrobial activity of two novel perylene diimides which were synthesized and characterized. Antimicrobial activity was investigated against Four Mycobacterium tuberculosis strains (MT) (Mt-H37Rv, Mt-H37Ra and two clinical isolates) and two Staphylococcus aureus strains [Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA)]. Minimum inhibitory concentrations (MICs) and minimum bactericidal activity (MBCs) were determined. Both compounds exhibited bactericidal effects and MICs were found to be changing in the range of 48-96 µg/mL for four MT-strains. Compounds were also effective on Staphylococcus strains at MIC = 96 µg/mL. |
| first_indexed | 2024-03-12T01:42:13Z |
| format | Article |
| id | doaj.art-3c0b4e885d4b4186aaeba97ed8d70a89 |
| institution | Directory Open Access Journal |
| issn | 2149-0120 |
| language | English |
| last_indexed | 2024-03-12T01:42:13Z |
| publishDate | 2023-08-01 |
| publisher | Turkish Chemical Society |
| record_format | Article |
| series | Journal of the Turkish Chemical Society, Section A: Chemistry |
| spelling | doaj.art-3c0b4e885d4b4186aaeba97ed8d70a892023-09-10T07:27:45ZengTurkish Chemical SocietyJournal of the Turkish Chemical Society, Section A: Chemistry2149-01202023-08-01103633640https://doi.org/10.18596/jotcsa.1292068Novel Perylene-Based Antimicrobial PDI ChromophoresCansu YILMAZ0https://orcid.org/0009-0004-6647-9808Pınar GÜNER1https://orcid.org/0000-0001-6922-7009Tülin AŞKUN2https://orcid.org/0000-0002-2700-1965Funda YÜKRÜK3https://orcid.org/0000-0002-0460-0834 Balıkesir Üniversitesi Balıkesir Üniversitesi Balıkesir Üniversitesi Balikesir University The main goal of the study was to monitor the Antimicrobial activity of two novel perylene diimides which were synthesized and characterized. Antimicrobial activity was investigated against Four Mycobacterium tuberculosis strains (MT) (Mt-H37Rv, Mt-H37Ra and two clinical isolates) and two Staphylococcus aureus strains [Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA)]. Minimum inhibitory concentrations (MICs) and minimum bactericidal activity (MBCs) were determined. Both compounds exhibited bactericidal effects and MICs were found to be changing in the range of 48-96 µg/mL for four MT-strains. Compounds were also effective on Staphylococcus strains at MIC = 96 µg/mL.https://dergipark.org.tr/tr/pub/jotcsa/issue/78393/1292068perylene diimideantimicrobial activitymycobacterium tuberculosismethicillin resistantstaphylococcus aureusmicmbc |
| spellingShingle | Cansu YILMAZ Pınar GÜNER Tülin AŞKUN Funda YÜKRÜK Novel Perylene-Based Antimicrobial PDI Chromophores Journal of the Turkish Chemical Society, Section A: Chemistry perylene diimide antimicrobial activity mycobacterium tuberculosis methicillin resistant staphylococcus aureus mic mbc |
| title | Novel Perylene-Based Antimicrobial PDI Chromophores |
| title_full | Novel Perylene-Based Antimicrobial PDI Chromophores |
| title_fullStr | Novel Perylene-Based Antimicrobial PDI Chromophores |
| title_full_unstemmed | Novel Perylene-Based Antimicrobial PDI Chromophores |
| title_short | Novel Perylene-Based Antimicrobial PDI Chromophores |
| title_sort | novel perylene based antimicrobial pdi chromophores |
| topic | perylene diimide antimicrobial activity mycobacterium tuberculosis methicillin resistant staphylococcus aureus mic mbc |
| url | https://dergipark.org.tr/tr/pub/jotcsa/issue/78393/1292068 |
| work_keys_str_mv | AT cansuyilmaz novelperylenebasedantimicrobialpdichromophores AT pınarguner novelperylenebasedantimicrobialpdichromophores AT tulinaskun novelperylenebasedantimicrobialpdichromophores AT fundayukruk novelperylenebasedantimicrobialpdichromophores |