Drug-induced lung disease due to topical minoxidil
A 55-year-old man presented to our institution with abnormal chest X-ray shadows. Chest computed tomography (CT) showed left-sided interlobular septal thickening; thus, we suspected lymphangitis carcinomatosis and other disorders that show similar CT findings. Bronchoscopy and laboratory and imaging...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007123001351 |
| _version_ | 1797382839375757312 |
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| author | Takashi Ishiguro Yoichi Kobayashi Hajime Furuno Naomi Takata Yoshinori Kawabata Yoshihiko Shimizu Yotaro Takaku |
| author_facet | Takashi Ishiguro Yoichi Kobayashi Hajime Furuno Naomi Takata Yoshinori Kawabata Yoshihiko Shimizu Yotaro Takaku |
| author_sort | Takashi Ishiguro |
| collection | DOAJ |
| description | A 55-year-old man presented to our institution with abnormal chest X-ray shadows. Chest computed tomography (CT) showed left-sided interlobular septal thickening; thus, we suspected lymphangitis carcinomatosis and other disorders that show similar CT findings. Bronchoscopy and laboratory and imaging studies yielded no diagnostic findings. Pulmonary shadows during follow-up spontaneously improved then worsened. Thoracoscopic lung biopsy samples showed interstitial pneumonia and granulomas but the etiology of the pulmonary lesion could not be determined. At seven years after presentation, the patient's pulmonary shadows had gradually deteriorated, and he reported using topical minoxidil. His history of minoxidil use was linked to changes in the pulmonary shadows. The diagnostic delay was due to the patient's hesitancy to report drugs obtained online and the difficulty in obtaining such a history. |
| first_indexed | 2024-03-08T21:12:11Z |
| format | Article |
| id | doaj.art-3c0f51bbd9cc4b1f83583e0a412b1ad5 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-03-08T21:12:11Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-3c0f51bbd9cc4b1f83583e0a412b1ad52023-12-22T05:32:57ZengElsevierRespiratory Medicine Case Reports2213-00712023-01-0146101940Drug-induced lung disease due to topical minoxidilTakashi Ishiguro0Yoichi Kobayashi1Hajime Furuno2Naomi Takata3Yoshinori Kawabata4Yoshihiko Shimizu5Yotaro Takaku6Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan; Corresponding author.Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, JapanDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, JapanDepartment of Radiology, Saitama Cardiovascular and Respiratory Center, Saitama, JapanDepartment of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, JapanDepartment of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, JapanDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, JapanA 55-year-old man presented to our institution with abnormal chest X-ray shadows. Chest computed tomography (CT) showed left-sided interlobular septal thickening; thus, we suspected lymphangitis carcinomatosis and other disorders that show similar CT findings. Bronchoscopy and laboratory and imaging studies yielded no diagnostic findings. Pulmonary shadows during follow-up spontaneously improved then worsened. Thoracoscopic lung biopsy samples showed interstitial pneumonia and granulomas but the etiology of the pulmonary lesion could not be determined. At seven years after presentation, the patient's pulmonary shadows had gradually deteriorated, and he reported using topical minoxidil. His history of minoxidil use was linked to changes in the pulmonary shadows. The diagnostic delay was due to the patient's hesitancy to report drugs obtained online and the difficulty in obtaining such a history.http://www.sciencedirect.com/science/article/pii/S2213007123001351Drug-induced lung diseaseMinoxidilGranulomaTopical useInterlobular septal thickening |
| spellingShingle | Takashi Ishiguro Yoichi Kobayashi Hajime Furuno Naomi Takata Yoshinori Kawabata Yoshihiko Shimizu Yotaro Takaku Drug-induced lung disease due to topical minoxidil Respiratory Medicine Case Reports Drug-induced lung disease Minoxidil Granuloma Topical use Interlobular septal thickening |
| title | Drug-induced lung disease due to topical minoxidil |
| title_full | Drug-induced lung disease due to topical minoxidil |
| title_fullStr | Drug-induced lung disease due to topical minoxidil |
| title_full_unstemmed | Drug-induced lung disease due to topical minoxidil |
| title_short | Drug-induced lung disease due to topical minoxidil |
| title_sort | drug induced lung disease due to topical minoxidil |
| topic | Drug-induced lung disease Minoxidil Granuloma Topical use Interlobular septal thickening |
| url | http://www.sciencedirect.com/science/article/pii/S2213007123001351 |
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