Upregulation of the PatAB Transporter Confers Fluoroquinolone Resistance to Streptococcus pseudopneumoniae

Upregulation of the PatAB Transporter Confers Fluoroquinolone Resistance to Streptococcus pseudopneumoniae

We characterized the mechanism of fluoroquinolone-resistance in two isolates of Streptococcus pseudopneumoniae having fluoroquinolone-efflux as unique mechanism of resistance. Whole genome sequencing and genetic transformation experiments were performed together with phenotypic determinations of the...

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Bibliographic Details
Main Authors:	María Alvarado, Antonio J. Martín-Galiano, María J. Ferrándiz, Ángel Zaballos, Adela G. de la Campa
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Series:	Frontiers in Microbiology
Subjects:	DNA topoisomerases efflux pumps fluoroquinolones transcription regulation Streptococcus pseudopneumoniae
Online Access:	http://journal.frontiersin.org/article/10.3389/fmicb.2017.02074/full

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