The Clinical Value of Measuring Circulating HPV DNA during Chemo-Radiotherapy in Squamous Cell Carcinoma of the Anus

The Clinical Value of Measuring Circulating HPV DNA during Chemo-Radiotherapy in Squamous Cell Carcinoma of the Anus

Background and purpose: Circulating tumor DNA (ctDNA) is investigated in various cancers. In squamous cell carcinoma of the anus (SCCA) infection with human papilloma virus (HPV) is found in around 90% of cases and here, plasma HPV (pHPV) can be used as ctDNA. Preliminary data have proved the abilit...

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Bibliographic Details
Main Authors: Anna C. Lefèvre, Niels Pallisgaard, Camilla Kronborg, Karen L. Wind, Søren R. P. Krag, Karen-Lise G. Spindler
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
anus neoplasms
squamous cell carcinoma
human papillomavirus
circulating tumor DNA
Online Access:https://www.mdpi.com/2072-6694/13/10/2451

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