Prophylactic administration of tranexamic acid combined with thromboelastography-guided hemostatic algorithm reduces allogeneic transfusion requirements during pediatric resective epilepsy surgery: A randomized controlled trial

Prophylactic administration of tranexamic acid combined with thromboelastography-guided hemostatic algorithm reduces allogeneic transfusion requirements during pediatric resective epilepsy surgery: A randomized controlled trial

Background: Intraoperative bleeding and allogeneic transfusion remain common problems in pediatric resective epilepsy surgery. Tranexamic acid (TXA) is a widely recommended antifibrinolytic drug that reduces blood loss and transfusion requirements for bleeding patients. Thromboelastography (TEG)-gui...

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Bibliographic Details
Main Authors:	Ting Zhang, Hua Feng, Wei Xiao, Jingsheng Li, Qinghai Liu, Xuexin Feng, Dezhou Qi, Xiaotong Fan, Yongzhi Shan, Tao Yu, Guoguang Zhao, Tianlong Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Pharmacology
Subjects:	tranexamic acid antifibrinolytics thromboelastography epilepsy surgery pediatric anesthesia transfusion
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.916017/full

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