Applications of paper as a support material in biomedical sciences: A decadal review
In human history, the paper has long been used as a platform to record and preserve information. However, over the decades, paper has found its application in Biomedical Sciences, too. Both paper-based microfluidic devices (μPADs) and paper-based cultures and scaffolds have shown immense potential t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2020-01-01
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| Series: | Sensors International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666351120300048 |
| _version_ | 1818321189862375424 |
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| author | Bimalendu Deka Rima Kalita Dinesh Bhatia Animesh Mishra |
| author_facet | Bimalendu Deka Rima Kalita Dinesh Bhatia Animesh Mishra |
| author_sort | Bimalendu Deka |
| collection | DOAJ |
| description | In human history, the paper has long been used as a platform to record and preserve information. However, over the decades, paper has found its application in Biomedical Sciences, too. Both paper-based microfluidic devices (μPADs) and paper-based cultures and scaffolds have shown immense potential to be used as a sensor as well as a supporting material for in vitro tissue engineering. μPADs can be used to perform low-cost and fast biomolecular assays at Point-Of-Care (POC). They are being used to detect various biomarkers like viral proteins, metabolites, oncogenes, and antigens; and conditions like Venous Thromboembolism (VTE). On the other hand, the paper has also been used to develop paper-based 3D cultures and scaffolds to test drugs, and monitor cytotoxic effects in vitro cell microenvironments and also as implantable tissues. In this review, we intend to enumerate the development in the field of μPADs, paper-based cell cultures, and paper-based scaffolds and their plethora of applications over the last decade. |
| first_indexed | 2024-12-13T10:36:57Z |
| format | Article |
| id | doaj.art-3c1df7c2ddb14e26bd37f581758796a8 |
| institution | Directory Open Access Journal |
| issn | 2666-3511 |
| language | English |
| last_indexed | 2024-12-13T10:36:57Z |
| publishDate | 2020-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Sensors International |
| spelling | doaj.art-3c1df7c2ddb14e26bd37f581758796a82022-12-21T23:50:41ZengKeAi Communications Co., Ltd.Sensors International2666-35112020-01-011100004Applications of paper as a support material in biomedical sciences: A decadal reviewBimalendu Deka0Rima Kalita1Dinesh Bhatia2Animesh Mishra3Department of Biomedical Engineering, North Eastern Hill University, Shillong, 793022, Meghalaya, IndiaDepartment of Biomedical Engineering, North Eastern Hill University, Shillong, 793022, Meghalaya, IndiaDepartment of Biomedical Engineering, North Eastern Hill University, Shillong, 793022, Meghalaya, India; Corresponding author.Department of Cardiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, 793018, Meghalaya, IndiaIn human history, the paper has long been used as a platform to record and preserve information. However, over the decades, paper has found its application in Biomedical Sciences, too. Both paper-based microfluidic devices (μPADs) and paper-based cultures and scaffolds have shown immense potential to be used as a sensor as well as a supporting material for in vitro tissue engineering. μPADs can be used to perform low-cost and fast biomolecular assays at Point-Of-Care (POC). They are being used to detect various biomarkers like viral proteins, metabolites, oncogenes, and antigens; and conditions like Venous Thromboembolism (VTE). On the other hand, the paper has also been used to develop paper-based 3D cultures and scaffolds to test drugs, and monitor cytotoxic effects in vitro cell microenvironments and also as implantable tissues. In this review, we intend to enumerate the development in the field of μPADs, paper-based cell cultures, and paper-based scaffolds and their plethora of applications over the last decade.http://www.sciencedirect.com/science/article/pii/S2666351120300048μPADPaperDiagnosisPaper-based-cultureScaffold |
| spellingShingle | Bimalendu Deka Rima Kalita Dinesh Bhatia Animesh Mishra Applications of paper as a support material in biomedical sciences: A decadal review Sensors International μPAD Paper Diagnosis Paper-based-culture Scaffold |
| title | Applications of paper as a support material in biomedical sciences: A decadal review |
| title_full | Applications of paper as a support material in biomedical sciences: A decadal review |
| title_fullStr | Applications of paper as a support material in biomedical sciences: A decadal review |
| title_full_unstemmed | Applications of paper as a support material in biomedical sciences: A decadal review |
| title_short | Applications of paper as a support material in biomedical sciences: A decadal review |
| title_sort | applications of paper as a support material in biomedical sciences a decadal review |
| topic | μPAD Paper Diagnosis Paper-based-culture Scaffold |
| url | http://www.sciencedirect.com/science/article/pii/S2666351120300048 |
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