Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement
An unusual and well-characterised case of composite lymphoma in the spleen and lymph node is presented. The simultaneous occurrence of mixed-cellularity Hodgkin's lymphoma (HL) and follicular non-Hodgkin's lymphoma (NHL) was demonstrated in a 66-year-old man admitted in our Service with an...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Patologia Clínica
2004-01-01
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| Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100008 |
| _version_ | 1818939921705992192 |
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| author | Grangeiro Maria do Patrocínio F. Magalhães Sílvia Maria M. Ferreira Francisco Valdeci A. Rocha Filho Francisco Dário |
| author_facet | Grangeiro Maria do Patrocínio F. Magalhães Sílvia Maria M. Ferreira Francisco Valdeci A. Rocha Filho Francisco Dário |
| author_sort | Grangeiro Maria do Patrocínio F. |
| collection | DOAJ |
| description | An unusual and well-characterised case of composite lymphoma in the spleen and lymph node is presented. The simultaneous occurrence of mixed-cellularity Hodgkin's lymphoma (HL) and follicular non-Hodgkin's lymphoma (NHL) was demonstrated in a 66-year-old man admitted in our Service with anaemia, hepatosplenomegaly and multiple abdominal lymph nodes. The morphological study of the spleen and lymph node of the splenic hilum showed an infiltrate composed of two distinct neoplasias. The liver was involved by NHL infiltrate and the peripancreatic lymph node exhibited HL. The Reed-Sternberg (RS) cells expressed CD 15 and CD 30, whereas the NHL cells presented standard immunohistochemical features of follicular lymphoma. To our knowledge, this is the fifth case report of concurrent spleen involvement by composite lymphoma. The incidence, clinicopathological and immunohistochemical features of this rare association are discussed. |
| first_indexed | 2024-12-20T06:31:26Z |
| format | Article |
| id | doaj.art-3c1f1b21b7b840558290029756172cd0 |
| institution | Directory Open Access Journal |
| issn | 1676-2444 1678-4774 |
| language | English |
| last_indexed | 2024-12-20T06:31:26Z |
| publishDate | 2004-01-01 |
| publisher | Sociedade Brasileira de Patologia Clínica |
| record_format | Article |
| series | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| spelling | doaj.art-3c1f1b21b7b840558290029756172cd02022-12-21T19:50:07ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1676-24441678-47742004-01-014013336Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvementGrangeiro Maria do Patrocínio F.Magalhães Sílvia Maria M.Ferreira Francisco Valdeci A.Rocha Filho Francisco DárioAn unusual and well-characterised case of composite lymphoma in the spleen and lymph node is presented. The simultaneous occurrence of mixed-cellularity Hodgkin's lymphoma (HL) and follicular non-Hodgkin's lymphoma (NHL) was demonstrated in a 66-year-old man admitted in our Service with anaemia, hepatosplenomegaly and multiple abdominal lymph nodes. The morphological study of the spleen and lymph node of the splenic hilum showed an infiltrate composed of two distinct neoplasias. The liver was involved by NHL infiltrate and the peripancreatic lymph node exhibited HL. The Reed-Sternberg (RS) cells expressed CD 15 and CD 30, whereas the NHL cells presented standard immunohistochemical features of follicular lymphoma. To our knowledge, this is the fifth case report of concurrent spleen involvement by composite lymphoma. The incidence, clinicopathological and immunohistochemical features of this rare association are discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100008Composite lymphomaSpleenLymph nodeFollicular lymphomaHodgkin's lymphoma |
| spellingShingle | Grangeiro Maria do Patrocínio F. Magalhães Sílvia Maria M. Ferreira Francisco Valdeci A. Rocha Filho Francisco Dário Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement Jornal Brasileiro de Patologia e Medicina Laboratorial Composite lymphoma Spleen Lymph node Follicular lymphoma Hodgkin's lymphoma |
| title | Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement |
| title_full | Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement |
| title_fullStr | Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement |
| title_full_unstemmed | Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement |
| title_short | Simultaneous occurrence of follicular lymphoma and mixed-cellularity Hodgkin's lymphoma: lymph node and extranodal involvement |
| title_sort | simultaneous occurrence of follicular lymphoma and mixed cellularity hodgkin s lymphoma lymph node and extranodal involvement |
| topic | Composite lymphoma Spleen Lymph node Follicular lymphoma Hodgkin's lymphoma |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100008 |
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