Prospects of using C3435T polymorphism in the <i>ABCB1</i> gene encoding P-glycoprotein in personalised medicine

Prospects of using C3435T polymorphism in the <i>ABCB1</i> gene encoding P-glycoprotein in personalised medicine

The article reviews scientific literature on C3435T polymorphism in the ABCB1 gene which encodes P-glycoprotein (an ATP-binding cassette transporter which is responsible for energy-dependent transport of substrates across cellular membranes and whose primary role consists in the prevention of penetr...

Full description

Bibliographic Details
Main Authors: R. E. Kazakov, V. A. Evteev, O. V. Muslimova, I. A. Mazerkina, E. Yu. Demchenkova, E. V. Shikh
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
персонализированная медицина
генетический полиморфизм
p-гликопротеин
однонуклеотидные полиморфизмы
атф-связывающие кассетные транспортеры
personalised medicine
genetic polymorphism
p-glycoprotein
single nucleotide polymorphisms
atp-binding cassette transporters
Online Access:https://www.vedomostincesmp.ru/jour/article/view/143

Internet

https://www.vedomostincesmp.ru/jour/article/view/143

Similar Items