APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION

The effectiveness of perftoran and recombinant superoxide dismutase in complex post-operative therapy in patients with acute intestinal obstruction was investigated. All patients (two groups) were combined. 49 patients received traditional complex therapy, 42 patients during the operation were given...

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Main Authors: D. V. Volkov, V. S. Tarasenko, S. I. Krasikov, N. V. Sharapova
Format: Article
Language:English
Published: Bashkir State Medical University 2017-01-01
Series:Креативная хирургия и онкология
Subjects:
Online Access:https://www.surgonco.ru/jour/article/view/32
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author D. V. Volkov
V. S. Tarasenko
S. I. Krasikov
N. V. Sharapova
author_facet D. V. Volkov
V. S. Tarasenko
S. I. Krasikov
N. V. Sharapova
author_sort D. V. Volkov
collection DOAJ
description The effectiveness of perftoran and recombinant superoxide dismutase in complex post-operative therapy in patients with acute intestinal obstruction was investigated. All patients (two groups) were combined. 49 patients received traditional complex therapy, 42 patients during the operation were given additional intravenous infusion recombinant superoxide dismutase and perftoran. Leucocyte intoxication index, the concentration of middle-weight molecules, dien conjugats and malone dialdehyde in serum, iron-induced and spontaneous chemiluminescence of blood serum, superoxide dismutase activity and catalase of erythrocyte at all patients were determined. It was established application of the perftoran and recombinant superoxide dismutase promotes the decrease of free-radical processes intensity, the reduction of endogenous intoxication and reduces the risk of the evident intestinal insufficiency development in patients with acute intestinal obstruction.
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spelling doaj.art-3c2249df5695407bb688aac75ebd474e2025-03-12T07:05:47ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012017-01-0103636710.24060/2076-3093-2014-0-3-63-6732APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTIOND. V. Volkov0V. S. Tarasenko1S. I. Krasikov2N. V. Sharapova3Orenburg State Medical AcademyOrenburg State Medical AcademyOrenburg State Medical AcademyOrenburg State Medical AcademyThe effectiveness of perftoran and recombinant superoxide dismutase in complex post-operative therapy in patients with acute intestinal obstruction was investigated. All patients (two groups) were combined. 49 patients received traditional complex therapy, 42 patients during the operation were given additional intravenous infusion recombinant superoxide dismutase and perftoran. Leucocyte intoxication index, the concentration of middle-weight molecules, dien conjugats and malone dialdehyde in serum, iron-induced and spontaneous chemiluminescence of blood serum, superoxide dismutase activity and catalase of erythrocyte at all patients were determined. It was established application of the perftoran and recombinant superoxide dismutase promotes the decrease of free-radical processes intensity, the reduction of endogenous intoxication and reduces the risk of the evident intestinal insufficiency development in patients with acute intestinal obstruction.https://www.surgonco.ru/jour/article/view/32acute intestinal obstructionenteral insufficiencyperftoransuperoxide dismutase
spellingShingle D. V. Volkov
V. S. Tarasenko
S. I. Krasikov
N. V. Sharapova
APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
Креативная хирургия и онкология
acute intestinal obstruction
enteral insufficiency
perftoran
superoxide dismutase
title APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
title_full APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
title_fullStr APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
title_full_unstemmed APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
title_short APPLICATION OF PERFTORAN AND RECOMBINANT SUPEROXIDE DISMUTASE IN COMPLEX TREATMENT OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION
title_sort application of perftoran and recombinant superoxide dismutase in complex treatment of enteral insufficiency in patients with acute intestinal obstruction
topic acute intestinal obstruction
enteral insufficiency
perftoran
superoxide dismutase
url https://www.surgonco.ru/jour/article/view/32
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AT sikrasikov applicationofperftoranandrecombinantsuperoxidedismutaseincomplextreatmentofenteralinsufficiencyinpatientswithacuteintestinalobstruction
AT nvsharapova applicationofperftoranandrecombinantsuperoxidedismutaseincomplextreatmentofenteralinsufficiencyinpatientswithacuteintestinalobstruction