http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf
2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules. In myocytes and pericytes, Ca2+ signals arise exclusively from Ca2+...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2013-12-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Burdyga_6_13.pdf |
| _version_ | 1827614089318236160 |
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| author | T. Burdyga L. Borysova |
| author_facet | T. Burdyga L. Borysova |
| author_sort | T. Burdyga |
| collection | DOAJ |
| description | 2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules. In myocytes and pericytes, Ca2+ signals arise exclusively from Ca2+ release from the sarcoplasmic reticulum through inositol 1,4,5-trisphosphate receptors. Са2+ transients in pericytes are less oscillatory, slower and longer-lasting than those in myocytes. The data obtained suggest differences in the mechanisms controlling local blood flow in precapillary arterioles and postcapillary venules. |
| first_indexed | 2024-03-09T08:49:49Z |
| format | Article |
| id | doaj.art-3c23c257f7094bc68da9b016bacf7a1b |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-09T08:49:49Z |
| publishDate | 2013-12-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-3c23c257f7094bc68da9b016bacf7a1b2023-12-02T14:35:56ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032013-12-0185612913310.15407/ubj85.06.129http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdfT. Burdyga0 L. Borysova1Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UKDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules. In myocytes and pericytes, Ca2+ signals arise exclusively from Ca2+ release from the sarcoplasmic reticulum through inositol 1,4,5-trisphosphate receptors. Са2+ transients in pericytes are less oscillatory, slower and longer-lasting than those in myocytes. The data obtained suggest differences in the mechanisms controlling local blood flow in precapillary arterioles and postcapillary venules.http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Burdyga_6_13.pdfCa(2+) signallingconfocal microscopymicrovascular networksmyocytespericytes |
| spellingShingle | T. Burdyga L. Borysova http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf The Ukrainian Biochemical Journal Ca(2+) signalling confocal microscopy microvascular networks myocytes pericytes |
| title | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf |
| title_full | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf |
| title_fullStr | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf |
| title_full_unstemmed | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf |
| title_short | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf |
| title_sort | http ukrbiochemjournal org wp content uploads 2015 11 kosterin 6 13 pdf |
| topic | Ca(2+) signalling confocal microscopy microvascular networks myocytes pericytes |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Burdyga_6_13.pdf |
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