Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity
We describe a case of wound botulism initially thought to represent Miller-Fisher variant Guillain-Barré syndrome (MFS). Botulism classically presents with the so-called “four D’s” (diplopia, dysarthria, dysphagia, dry mouth) with symmetric, descending weakness. MFS presents with a triad of limb-ata...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
eScholarship Publishing, University of California
2017-07-01
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| Series: | Clinical Practice and Cases in Emergency Medicine |
| Online Access: | https://escholarship.org/uc/item/3vb623mh |
| _version_ | 1819141928882536448 |
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| author | Daniel Z. Adams Andrew King Colin Kaide |
| author_facet | Daniel Z. Adams Andrew King Colin Kaide |
| author_sort | Daniel Z. Adams |
| collection | DOAJ |
| description | We describe a case of wound botulism initially thought to represent Miller-Fisher variant Guillain-Barré syndrome (MFS). Botulism classically presents with the so-called “four D’s” (diplopia, dysarthria, dysphagia, dry mouth) with symmetric, descending weakness. MFS presents with a triad of limb-ataxia, areflexia, and ophthalmoplegia, with variable cranial nerve and extremity involvement. The distinction can be difficult but is important as early initiation of botulinum antitoxin is associated with improved patient outcomes in cases of botulism. Furthermore, it is important to recognize intravenous drug use as a risk factor in the development of botulism, especially given an increase in injection drug use. |
| first_indexed | 2024-12-22T12:02:15Z |
| format | Article |
| id | doaj.art-3c249af081b445088c0e69fa38a0510a |
| institution | Directory Open Access Journal |
| issn | 2474-252X |
| language | English |
| last_indexed | 2024-12-22T12:02:15Z |
| publishDate | 2017-07-01 |
| publisher | eScholarship Publishing, University of California |
| record_format | Article |
| series | Clinical Practice and Cases in Emergency Medicine |
| spelling | doaj.art-3c249af081b445088c0e69fa38a0510a2022-12-21T18:26:34ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2017-07-011310.5811/cpcem.2017.4.33728cpcem-01-238Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken IdentityDaniel Z. AdamsAndrew KingColin KaideWe describe a case of wound botulism initially thought to represent Miller-Fisher variant Guillain-Barré syndrome (MFS). Botulism classically presents with the so-called “four D’s” (diplopia, dysarthria, dysphagia, dry mouth) with symmetric, descending weakness. MFS presents with a triad of limb-ataxia, areflexia, and ophthalmoplegia, with variable cranial nerve and extremity involvement. The distinction can be difficult but is important as early initiation of botulinum antitoxin is associated with improved patient outcomes in cases of botulism. Furthermore, it is important to recognize intravenous drug use as a risk factor in the development of botulism, especially given an increase in injection drug use.https://escholarship.org/uc/item/3vb623mh |
| spellingShingle | Daniel Z. Adams Andrew King Colin Kaide Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity Clinical Practice and Cases in Emergency Medicine |
| title | Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity |
| title_full | Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity |
| title_fullStr | Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity |
| title_full_unstemmed | Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity |
| title_short | Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity |
| title_sort | cranial neuropathies and neuromuscular weakness a case of mistaken identity |
| url | https://escholarship.org/uc/item/3vb623mh |
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