A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells
Background: The mechanism of argon laser retinal photocoagulation (ALRP) treatment is to apply thermal-induced retinal pigment epithelium damage. Light passes through the anterior optical segments of the eye to reach the retina. Lens densitometry is a noninvasive and quantitative measurement providi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-07-01
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| Series: | Therapeutic Advances in Ophthalmology |
| Online Access: | https://doi.org/10.1177/25158414231189071 |
| _version_ | 1827892477003038720 |
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| author | Uğur Yılmaz Hüseyin Kaya Selen Akbulut Yasin Durkal |
| author_facet | Uğur Yılmaz Hüseyin Kaya Selen Akbulut Yasin Durkal |
| author_sort | Uğur Yılmaz |
| collection | DOAJ |
| description | Background: The mechanism of argon laser retinal photocoagulation (ALRP) treatment is to apply thermal-induced retinal pigment epithelium damage. Light passes through the anterior optical segments of the eye to reach the retina. Lens densitometry is a noninvasive and quantitative measurement providing information about corneal and lens clarity. Objectives: This study aimed to investigate whether laser light affects lens clarity and corneal endothelial cells. Design: This was a prospective, cross-sectional study. Methods: Lens densitometric (LD) analysis and specular microscopy were performed before, after, and 1 month after ALRP treatment, by an expert ophthalmologist, blinded to the medical status of the patients. LD analysis was performed using a Pentacam HR (Oculus, Wetzlar, Germany) and a Specular Microscope CEM-530 (Nidek, Japan) was used for endothelial cell analysis. Results: The evaluation was made on 81 eyes of 41 patients, with a mean age of 54.46 ± 6.7 years. LD, after ALRP, was significantly more than before ALRP ( p < 0.001). There was no statistically significant difference in LD, before ALRP, and 1 month after ALRP ( p = 0.262). There was a statistically significant increase in LD after ALRP compared to before ALRP, but it decreased after 1 month. There was an increase in the coefficient of variance (CV) after ALRP compared to before ALRP but it was not statistically significant ( p = 0.188). There was no statistically significant difference in CV between before ALRP and 1 month after ALRP ( p = 1.000). There was no statistically significant difference in the cell density, the hexagonality percentage between before ALRP, after ALRP, and 1 month after ALRP ( p = 0.993, and 0.863, respectively). Conclusion: ALRP may affect the lens densitometry temporarily during the procedure. Thermal damage may be the reason for increased lens densitometry. |
| first_indexed | 2024-03-12T21:40:15Z |
| format | Article |
| id | doaj.art-3c2770ef59f649fc9abcc8f60b46b672 |
| institution | Directory Open Access Journal |
| issn | 2515-8414 |
| language | English |
| last_indexed | 2024-03-12T21:40:15Z |
| publishDate | 2023-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Ophthalmology |
| spelling | doaj.art-3c2770ef59f649fc9abcc8f60b46b6722023-07-27T01:04:49ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142023-07-011510.1177/25158414231189071A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cellsUğur YılmazHüseyin KayaSelen AkbulutYasin DurkalBackground: The mechanism of argon laser retinal photocoagulation (ALRP) treatment is to apply thermal-induced retinal pigment epithelium damage. Light passes through the anterior optical segments of the eye to reach the retina. Lens densitometry is a noninvasive and quantitative measurement providing information about corneal and lens clarity. Objectives: This study aimed to investigate whether laser light affects lens clarity and corneal endothelial cells. Design: This was a prospective, cross-sectional study. Methods: Lens densitometric (LD) analysis and specular microscopy were performed before, after, and 1 month after ALRP treatment, by an expert ophthalmologist, blinded to the medical status of the patients. LD analysis was performed using a Pentacam HR (Oculus, Wetzlar, Germany) and a Specular Microscope CEM-530 (Nidek, Japan) was used for endothelial cell analysis. Results: The evaluation was made on 81 eyes of 41 patients, with a mean age of 54.46 ± 6.7 years. LD, after ALRP, was significantly more than before ALRP ( p < 0.001). There was no statistically significant difference in LD, before ALRP, and 1 month after ALRP ( p = 0.262). There was a statistically significant increase in LD after ALRP compared to before ALRP, but it decreased after 1 month. There was an increase in the coefficient of variance (CV) after ALRP compared to before ALRP but it was not statistically significant ( p = 0.188). There was no statistically significant difference in CV between before ALRP and 1 month after ALRP ( p = 1.000). There was no statistically significant difference in the cell density, the hexagonality percentage between before ALRP, after ALRP, and 1 month after ALRP ( p = 0.993, and 0.863, respectively). Conclusion: ALRP may affect the lens densitometry temporarily during the procedure. Thermal damage may be the reason for increased lens densitometry.https://doi.org/10.1177/25158414231189071 |
| spellingShingle | Uğur Yılmaz Hüseyin Kaya Selen Akbulut Yasin Durkal A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells Therapeutic Advances in Ophthalmology |
| title | A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| title_full | A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| title_fullStr | A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| title_full_unstemmed | A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| title_short | A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| title_sort | cross sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells |
| url | https://doi.org/10.1177/25158414231189071 |
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