A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging

Deep learning has demonstrated remarkable accuracy analyzing images for cancer detection tasks in recent years. The accuracy that has been achieved rivals radiologists and is suitable for implementation as a clinical tool. However, a significant problem is that these models are black-box algorithms...

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Main Authors: Mehmet A. Gulum, Christopher M. Trombley, Mehmed Kantardzic
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/10/4573
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author Mehmet A. Gulum
Christopher M. Trombley
Mehmed Kantardzic
author_facet Mehmet A. Gulum
Christopher M. Trombley
Mehmed Kantardzic
author_sort Mehmet A. Gulum
collection DOAJ
description Deep learning has demonstrated remarkable accuracy analyzing images for cancer detection tasks in recent years. The accuracy that has been achieved rivals radiologists and is suitable for implementation as a clinical tool. However, a significant problem is that these models are black-box algorithms therefore they are intrinsically unexplainable. This creates a barrier for clinical implementation due to lack of trust and transparency that is a characteristic of black box algorithms. Additionally, recent regulations prevent the implementation of unexplainable models in clinical settings which further demonstrates a need for explainability. To mitigate these concerns, there have been recent studies that attempt to overcome these issues by modifying deep learning architectures or providing after-the-fact explanations. A review of the deep learning explanation literature focused on cancer detection using MR images is presented here. The gap between what clinicians deem explainable and what current methods provide is discussed and future suggestions to close this gap are provided.
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spelling doaj.art-3c2bb870137d4e758ad3bd37cf5b5a7e2023-11-21T20:06:36ZengMDPI AGApplied Sciences2076-34172021-05-011110457310.3390/app11104573A Review of Explainable Deep Learning Cancer Detection Models in Medical ImagingMehmet A. Gulum0Christopher M. Trombley1Mehmed Kantardzic2Computer Science & Engineering Department, J.B. Speed School of Engineering, University of Louisville, Louisville, KT 40292, USAComputer Science & Engineering Department, J.B. Speed School of Engineering, University of Louisville, Louisville, KT 40292, USAComputer Science & Engineering Department, J.B. Speed School of Engineering, University of Louisville, Louisville, KT 40292, USADeep learning has demonstrated remarkable accuracy analyzing images for cancer detection tasks in recent years. The accuracy that has been achieved rivals radiologists and is suitable for implementation as a clinical tool. However, a significant problem is that these models are black-box algorithms therefore they are intrinsically unexplainable. This creates a barrier for clinical implementation due to lack of trust and transparency that is a characteristic of black box algorithms. Additionally, recent regulations prevent the implementation of unexplainable models in clinical settings which further demonstrates a need for explainability. To mitigate these concerns, there have been recent studies that attempt to overcome these issues by modifying deep learning architectures or providing after-the-fact explanations. A review of the deep learning explanation literature focused on cancer detection using MR images is presented here. The gap between what clinicians deem explainable and what current methods provide is discussed and future suggestions to close this gap are provided.https://www.mdpi.com/2076-3417/11/10/4573deep learningexplanabilityexplainabilitycancer detectonMRIXAI
spellingShingle Mehmet A. Gulum
Christopher M. Trombley
Mehmed Kantardzic
A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
Applied Sciences
deep learning
explanability
explainability
cancer detecton
MRI
XAI
title A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
title_full A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
title_fullStr A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
title_full_unstemmed A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
title_short A Review of Explainable Deep Learning Cancer Detection Models in Medical Imaging
title_sort review of explainable deep learning cancer detection models in medical imaging
topic deep learning
explanability
explainability
cancer detecton
MRI
XAI
url https://www.mdpi.com/2076-3417/11/10/4573
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