| Summary: | Abstract Introduction As the quantity and complexity of health data grows, it is critical for healthcare organizations to devise analytic strategies that power data innovation so they can take advantage of new opportunities and improve outcomes. Seattle Children's Healthcare System (Seattle Children's) is an example of an organization that has built an operating model that integrates analytics into their business and daily operations. We present a roadmap for how Seattle Children's consolidated its fragmented analytics operations into a unified cohesive ecosystem capable of supporting advanced analytics capabilities and operational integration to transform care and accelerate research. Methods In‐depth interviews were conducted with ten leaders at Seattle Children's who have been instrumental in developing their enterprise analytics program. Interviews included the following leadership roles: Chief Data & Analytics Officer, Director of Research Informatics, Principal Systems Architect, Manager of Bioinformatics and High Throughput Analytics, Director of Neurocritical Care, Strategic Program Manager & Neuron Product Development Lead, Director of Dev Ops,Director of Clinical Analytics, Data Science Manager, and Advance Analytics Product Engineer. The interviews were unstructured and consisted of conversations intended to gather information from leadership about their experiences in building out Enterprise Analytics at Seattle Children's. Results Seattle Children's has built an advanced enterprise analytics ecosystem that is integrated into its daily operations by applying an entrepreneurial mindset and agile development practices that are common in a startup environment. Analytics efforts were approached iteratively by selecting high‐value projects that were delivered through Multidisciplinary Delivery Teams that were integrated into service lines. Service line leadership, in partnership with the Delivery Team leads, were responsible for the success of the team by setting project priorities, determining project budgets, and maintaining overall governance of their analytics endeavors. This organizational structure has led to the development of a wide range of analytic products that have been used to improve both operations and clinical care at Seattle Children's. Conclusions Seattle Children's has demonstrated how a leading healthcare system can successfully create a robust, scalable, near real‐time analytics ecosystem‐ one that delivers significant value to the organization from the ever‐expanding volume of health data we see today.
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