Modulating bacterial and gut mucosal interactions with engineered biofilm matrix proteins
Abstract Extracellular appendages play a significant role in mediating communication between bacteria and their host. Curli fibers are a class of bacterial fimbria that is highly amenable to engineering. We demonstrate the use of engineered curli fibers to rationally program interactions between bac...
Main Authors: | Anna M. Duraj-Thatte, Pichet Praveschotinunt, Trevor R. Nash, Frederick R. Ward, Neel S. Joshi |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-21834-8 |
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