An Optical Tweezers-Based Single-Cell Manipulation and Detection Platform for Probing Real-Time Cancer Cell Chemotaxis and Response to Tyrosine Kinase Inhibitor PD153035

An Optical Tweezers-Based Single-Cell Manipulation and Detection Platform for Probing Real-Time Cancer Cell Chemotaxis and Response to Tyrosine Kinase Inhibitor PD153035

We presented an approach to address cancer cell chemotaxis and response to tyrosine kinase inhibitor PD153035 at the single-cell level. We applied an optical tweezer system together with the platform at the single-cell level to manipulate an epidermal growth factor (EGF)-coated bead positioned close...

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Bibliographic Details
Main Authors: Pei-Wen Peng, Jen-Chang Yang, Mamadi M.S Colley, Tzu-Sen Yang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Photonics
Subjects:
chemotaxis
epidermal growth factor (EGF)
epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitor
PD153035
optical tweezers
Online Access:https://www.mdpi.com/2304-6732/8/12/533

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