Serotonin and dopamine modulate aging in response to food odor and availability
This report finds that dietary restriction, the most extensively studied anti-aging intervention, can be mimicked by blocking food odour signaling and identifies a neural network of food perception that functions through serotonin and dopamine.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-30869-5 |
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author | Hillary A. Miller Shijiao Huang Elizabeth S. Dean Megan L. Schaller Angela M. Tuckowski Allyson S. Munneke Safa Beydoun Scott D. Pletcher Scott F. Leiser |
author_facet | Hillary A. Miller Shijiao Huang Elizabeth S. Dean Megan L. Schaller Angela M. Tuckowski Allyson S. Munneke Safa Beydoun Scott D. Pletcher Scott F. Leiser |
author_sort | Hillary A. Miller |
collection | DOAJ |
description | This report finds that dietary restriction, the most extensively studied anti-aging intervention, can be mimicked by blocking food odour signaling and identifies a neural network of food perception that functions through serotonin and dopamine. |
first_indexed | 2024-04-12T15:20:24Z |
format | Article |
id | doaj.art-3c3039c8eb084652ba7863dcb8723819 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-12T15:20:24Z |
publishDate | 2022-06-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-3c3039c8eb084652ba7863dcb87238192022-12-22T03:27:27ZengNature PortfolioNature Communications2041-17232022-06-0113111310.1038/s41467-022-30869-5Serotonin and dopamine modulate aging in response to food odor and availabilityHillary A. Miller0Shijiao Huang1Elizabeth S. Dean2Megan L. Schaller3Angela M. Tuckowski4Allyson S. Munneke5Safa Beydoun6Scott D. Pletcher7Scott F. Leiser8Cellular and Molecular Biology Program, University of MichiganMolecular & Integrative Physiology Department, University of MichiganMolecular & Integrative Physiology Department, University of MichiganMolecular & Integrative Physiology Department, University of MichiganCellular and Molecular Biology Program, University of MichiganCellular and Molecular Biology Program, University of MichiganMolecular & Integrative Physiology Department, University of MichiganMolecular & Integrative Physiology Department, University of MichiganMolecular & Integrative Physiology Department, University of MichiganThis report finds that dietary restriction, the most extensively studied anti-aging intervention, can be mimicked by blocking food odour signaling and identifies a neural network of food perception that functions through serotonin and dopamine.https://doi.org/10.1038/s41467-022-30869-5 |
spellingShingle | Hillary A. Miller Shijiao Huang Elizabeth S. Dean Megan L. Schaller Angela M. Tuckowski Allyson S. Munneke Safa Beydoun Scott D. Pletcher Scott F. Leiser Serotonin and dopamine modulate aging in response to food odor and availability Nature Communications |
title | Serotonin and dopamine modulate aging in response to food odor and availability |
title_full | Serotonin and dopamine modulate aging in response to food odor and availability |
title_fullStr | Serotonin and dopamine modulate aging in response to food odor and availability |
title_full_unstemmed | Serotonin and dopamine modulate aging in response to food odor and availability |
title_short | Serotonin and dopamine modulate aging in response to food odor and availability |
title_sort | serotonin and dopamine modulate aging in response to food odor and availability |
url | https://doi.org/10.1038/s41467-022-30869-5 |
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