Biologics, theranostics, and personalized medicine in drug delivery systems
The progress in human disease treatment can be greatly advanced through the implementation of nanomedicine. This approach involves targeted and cell-specific therapy, controlled drug release, personalized dosage forms, wearable drug delivery, and companion diagnostics. By integrating cutting-edge te...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Pharmacological Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661824000306 |
| _version_ | 1797291821353664512 |
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| author | Matteo Puccetti Marilena Pariano Aurélie Schoubben Stefano Giovagnoli Maurizio Ricci |
| author_facet | Matteo Puccetti Marilena Pariano Aurélie Schoubben Stefano Giovagnoli Maurizio Ricci |
| author_sort | Matteo Puccetti |
| collection | DOAJ |
| description | The progress in human disease treatment can be greatly advanced through the implementation of nanomedicine. This approach involves targeted and cell-specific therapy, controlled drug release, personalized dosage forms, wearable drug delivery, and companion diagnostics. By integrating cutting-edge technologies with drug delivery systems, greater precision can be achieved at the tissue and cellular levels through the use of stimuli-responsive nanoparticles, and the development of electrochemical sensor systems. This precision targeting – by virtue of nanotechnology – allows for therapy to be directed specifically to affected tissues while greatly reducing side effects on healthy tissues. As such, nanomedicine has the potential to transform the treatment of conditions such as cancer, genetic diseases, and chronic illnesses by facilitating precise and cell-specific drug delivery. Additionally, personalized dosage forms and wearable devices offer the ability to tailor treatment to the unique needs of each patient, thereby increasing therapeutic effectiveness and compliance. Companion diagnostics further enable efficient monitoring of treatment response, enabling customized adjustments to the treatment plan. The question of whether all the potential therapeutic approaches outlined here are viable alternatives to current treatments is also discussed. In general, the application of nanotechnology in the field of biomedicine may provide a strong alternative to existing treatments for several reasons. In this review, we aim to present evidence that, although in early stages, fully merging advanced technology with innovative drug delivery shows promise for successful implementation across various disease areas, including cancer and genetic or chronic diseases. |
| first_indexed | 2024-03-07T19:42:21Z |
| format | Article |
| id | doaj.art-3c34222cbbbd4b6480dad03a49327f93 |
| institution | Directory Open Access Journal |
| issn | 1096-1186 |
| language | English |
| last_indexed | 2024-03-07T19:42:21Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research |
| spelling | doaj.art-3c34222cbbbd4b6480dad03a49327f932024-02-29T05:18:07ZengElsevierPharmacological Research1096-11862024-03-01201107086Biologics, theranostics, and personalized medicine in drug delivery systemsMatteo Puccetti0Marilena Pariano1Aurélie Schoubben2Stefano Giovagnoli3Maurizio Ricci4Department of Pharmaceutical Sciences, University of Perugia, Italy,; Corresponding authors.Department of Medicine and Surgery, University, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, Italy,Department of Pharmaceutical Sciences, University of Perugia, Italy,Department of Pharmaceutical Sciences, University of Perugia, Italy,; Corresponding authors.The progress in human disease treatment can be greatly advanced through the implementation of nanomedicine. This approach involves targeted and cell-specific therapy, controlled drug release, personalized dosage forms, wearable drug delivery, and companion diagnostics. By integrating cutting-edge technologies with drug delivery systems, greater precision can be achieved at the tissue and cellular levels through the use of stimuli-responsive nanoparticles, and the development of electrochemical sensor systems. This precision targeting – by virtue of nanotechnology – allows for therapy to be directed specifically to affected tissues while greatly reducing side effects on healthy tissues. As such, nanomedicine has the potential to transform the treatment of conditions such as cancer, genetic diseases, and chronic illnesses by facilitating precise and cell-specific drug delivery. Additionally, personalized dosage forms and wearable devices offer the ability to tailor treatment to the unique needs of each patient, thereby increasing therapeutic effectiveness and compliance. Companion diagnostics further enable efficient monitoring of treatment response, enabling customized adjustments to the treatment plan. The question of whether all the potential therapeutic approaches outlined here are viable alternatives to current treatments is also discussed. In general, the application of nanotechnology in the field of biomedicine may provide a strong alternative to existing treatments for several reasons. In this review, we aim to present evidence that, although in early stages, fully merging advanced technology with innovative drug delivery shows promise for successful implementation across various disease areas, including cancer and genetic or chronic diseases.http://www.sciencedirect.com/science/article/pii/S1043661824000306BiologicsInnovative delivery systemsTheranosticsNanomedicinePersonalized medicine |
| spellingShingle | Matteo Puccetti Marilena Pariano Aurélie Schoubben Stefano Giovagnoli Maurizio Ricci Biologics, theranostics, and personalized medicine in drug delivery systems Pharmacological Research Biologics Innovative delivery systems Theranostics Nanomedicine Personalized medicine |
| title | Biologics, theranostics, and personalized medicine in drug delivery systems |
| title_full | Biologics, theranostics, and personalized medicine in drug delivery systems |
| title_fullStr | Biologics, theranostics, and personalized medicine in drug delivery systems |
| title_full_unstemmed | Biologics, theranostics, and personalized medicine in drug delivery systems |
| title_short | Biologics, theranostics, and personalized medicine in drug delivery systems |
| title_sort | biologics theranostics and personalized medicine in drug delivery systems |
| topic | Biologics Innovative delivery systems Theranostics Nanomedicine Personalized medicine |
| url | http://www.sciencedirect.com/science/article/pii/S1043661824000306 |
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