Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes
Objective: There is no daily practical method for the diagnosis and follow-up of premature rupture of membranes (PPROM). In this study, we examined the association between PPROM and platelet/lymphocyte (PLR) and neutrophil/lymphocyte (NLR) ratios. Method: Eighty women with a diagnosis of PPROM betwe...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2024-03-01
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| Series: | Bagcilar Medical Bulletin |
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http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-neutrophil-lymphocyte-and-thrombocyt/64433
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| _version_ | 1797253830435405824 |
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| author | Yağmur Özkan Simten Genç Yücel Kaya Damla Yenlik Kaya Veli Mihmanlı |
| author_facet | Yağmur Özkan Simten Genç Yücel Kaya Damla Yenlik Kaya Veli Mihmanlı |
| author_sort | Yağmur Özkan |
| collection | DOAJ |
| description | Objective: There is no daily practical method for the diagnosis and follow-up of premature rupture of membranes (PPROM). In this study, we examined the association between PPROM and platelet/lymphocyte (PLR) and neutrophil/lymphocyte (NLR) ratios. Method: Eighty women with a diagnosis of PPROM between the 24th and 34th weeks of gestation were included in the study. Eighty-three women without membrane rupture between the same gestational weeks constituted the control group. Information about the women included in the study was collected retrospectively from hospital medical records. For each patient, gravida, parity, age, week of gestation, week of birth, and mode of delivery were examined. To evaluate perinatal outcomes, sex, 1st and 5th minute Apgar scores, birth weight, and neonatal death were examined. The patients’ white blood cells, lymphocyte neutrophil, and platelet counts, PLR, NLR ratios, hemoglobin, and C-reactive protein values were examined. Results: The mean NLR of the PPROM group was 30.96±2.55 [mean ± standard deviation (SD)] and mean PLR was 148.06±72.18 (mean ± SD). In the control group, these values were calculated as 30.91±2.43 (mean ± SD) and 126.74±45.85 (mean ± SD), respectively. Both rates were higher in the PPROM group (p=0.026). Conclusion: PLR and NLR ratios were higher in the study group. Therefore, PLR and NLR can be used in the management of PPROM. |
| first_indexed | 2024-04-24T21:40:18Z |
| format | Article |
| id | doaj.art-3c39c2822a72491698c93ebc7c687576 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-24T21:40:18Z |
| publishDate | 2024-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-3c39c2822a72491698c93ebc7c6875762024-03-21T06:27:24ZengGalenos YayineviBagcilar Medical Bulletin2547-94312024-03-019191410.4274/BMB.galenos.2024.2024-01-0613049054Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of MembranesYağmur Özkan0Simten Genç1Yücel Kaya2Damla Yenlik Kaya3Veli Mihmanlı4 Bahçelievler State Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Prof. Dr. Cemil Taşcıoğlu City Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, Antalya Training and Research Hospital, Clinic of Perinatology, Antalya, Turkey İstanbul Medipol University, Health Care Practice and Research Center, Esenler Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Prof. Dr. Cemil Taşcıoğlu City Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey Objective: There is no daily practical method for the diagnosis and follow-up of premature rupture of membranes (PPROM). In this study, we examined the association between PPROM and platelet/lymphocyte (PLR) and neutrophil/lymphocyte (NLR) ratios. Method: Eighty women with a diagnosis of PPROM between the 24th and 34th weeks of gestation were included in the study. Eighty-three women without membrane rupture between the same gestational weeks constituted the control group. Information about the women included in the study was collected retrospectively from hospital medical records. For each patient, gravida, parity, age, week of gestation, week of birth, and mode of delivery were examined. To evaluate perinatal outcomes, sex, 1st and 5th minute Apgar scores, birth weight, and neonatal death were examined. The patients’ white blood cells, lymphocyte neutrophil, and platelet counts, PLR, NLR ratios, hemoglobin, and C-reactive protein values were examined. Results: The mean NLR of the PPROM group was 30.96±2.55 [mean ± standard deviation (SD)] and mean PLR was 148.06±72.18 (mean ± SD). In the control group, these values were calculated as 30.91±2.43 (mean ± SD) and 126.74±45.85 (mean ± SD), respectively. Both rates were higher in the PPROM group (p=0.026). Conclusion: PLR and NLR ratios were higher in the study group. Therefore, PLR and NLR can be used in the management of PPROM. http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-neutrophil-lymphocyte-and-thrombocyt/64433 neutrophol/lymphocyte ratioplatelet/lymphocyte ratiopreterm premature rupture of fetal membranes |
| spellingShingle | Yağmur Özkan Simten Genç Yücel Kaya Damla Yenlik Kaya Veli Mihmanlı Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes Bagcilar Medical Bulletin neutrophol/lymphocyte ratio platelet/lymphocyte ratio preterm premature rupture of fetal membranes |
| title | Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes |
| title_full | Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes |
| title_fullStr | Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes |
| title_full_unstemmed | Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes |
| title_short | Evaluation of Neutrophil/Lymphocyte and Thrombocyte/Lymphocyte Ratios in Cases of Preterm Premature Rupture of Membranes |
| title_sort | evaluation of neutrophil lymphocyte and thrombocyte lymphocyte ratios in cases of preterm premature rupture of membranes |
| topic | neutrophol/lymphocyte ratio platelet/lymphocyte ratio preterm premature rupture of fetal membranes |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/evaluation-of-neutrophil-lymphocyte-and-thrombocyt/64433
|
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