The Effects of Lyophilization on the Physico-Chemical Stability of Sirolimus Liposomes
Purpose: The major limitation in the widespread use of liposome drug delivery system is its instability. Lyophilization is a promising approach to ensure the long-term stability of liposomes. The aim of this study was to prepare sirolimus-loaded liposomes, study their stability and investigate the e...
Main Authors: | Parvin Zakeri-Milani, Hadi Valizadeh, Saeed Ghanbarzadeh |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2013-02-01
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Series: | Advanced Pharmaceutical Bulletin |
Subjects: | |
Online Access: | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-25.pdf |
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