Activation of Canine, Mouse and Human TLR2 and TLR4 by Inactivated Leptospira Vaccine Strains

Activation of Canine, Mouse and Human TLR2 and TLR4 by Inactivated Leptospira Vaccine Strains

Canine Leptospira vaccines contain inactivated strains of pathogenic Leptospira, the causative agents of leptospirosis. For an effective response to vaccination, activation of the innate immune system via pattern recognition receptors such as TLRs is crucial. However, it is not known which TLRs are...

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Bibliographic Details
Main Authors: Andreja Novak, Elder Pupo, Esther van’t Veld, Victor P. M. G. Rutten, Femke Broere, Arjen Sloots
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
Leptospira
toll-like receptor
monocyte-derived dendritic cells
innate immunity
vaccine
canine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.823058/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.823058/full

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