Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture

In this study, we introduce the U-Swin fusion model, an effective and efficient transformer-based architecture designed for the fusion of multi-focus microscope images. We utilized the Swin-Transformer with shifted window and path merging as the encoder for extracted hierarchical context features. A...

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Main Authors: Han Hank Xia, Hao Gao, Hang Shao, Kun Gao, Wei Liu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/13/23/12798
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author Han Hank Xia
Hao Gao
Hang Shao
Kun Gao
Wei Liu
author_facet Han Hank Xia
Hao Gao
Hang Shao
Kun Gao
Wei Liu
author_sort Han Hank Xia
collection DOAJ
description In this study, we introduce the U-Swin fusion model, an effective and efficient transformer-based architecture designed for the fusion of multi-focus microscope images. We utilized the Swin-Transformer with shifted window and path merging as the encoder for extracted hierarchical context features. Additionally, a Swin-Transformer-based decoder with patch expansion was designed to perform the un-sampling operation, generating the fully focused image. To enhance the performance of the feature decoder, the skip connections were applied to concatenate the hierarchical features from the encoder with the decoder up-sample features, like U-net. To facilitate comprehensive model training, we created a substantial dataset of multi-focus images, primarily derived from texture datasets. Our modulators demonstrated superior capability for multi-focus image fusion to achieve comparable or even better fusion images than the existing state-of-the-art image fusion algorithms and demonstrated adequate generalization ability for multi-focus microscope image fusion. Remarkably, for multi-focus microscope image fusion, the pure transformer-based U-Swin fusion model incorporating channel mix fusion rules delivers optimal performance compared with most existing end-to-end fusion models.
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spelling doaj.art-3c3d07149f824cd3ab9ac7713c01657a2023-12-08T15:11:45ZengMDPI AGApplied Sciences2076-34172023-11-0113231279810.3390/app132312798Multi-Focus Microscopy Image Fusion Based on Swin Transformer ArchitectureHan Hank Xia0Hao Gao1Hang Shao2Kun Gao3Wei Liu4School of Electronic Science and Engineering, Nanjing University, Nanjing 210093, ChinaInstitute of Advanced Technology, Nanjing University of Posts and Telecommunications, Nanjing 210023, ChinaYangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, ChinaYangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, ChinaYangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, ChinaIn this study, we introduce the U-Swin fusion model, an effective and efficient transformer-based architecture designed for the fusion of multi-focus microscope images. We utilized the Swin-Transformer with shifted window and path merging as the encoder for extracted hierarchical context features. Additionally, a Swin-Transformer-based decoder with patch expansion was designed to perform the un-sampling operation, generating the fully focused image. To enhance the performance of the feature decoder, the skip connections were applied to concatenate the hierarchical features from the encoder with the decoder up-sample features, like U-net. To facilitate comprehensive model training, we created a substantial dataset of multi-focus images, primarily derived from texture datasets. Our modulators demonstrated superior capability for multi-focus image fusion to achieve comparable or even better fusion images than the existing state-of-the-art image fusion algorithms and demonstrated adequate generalization ability for multi-focus microscope image fusion. Remarkably, for multi-focus microscope image fusion, the pure transformer-based U-Swin fusion model incorporating channel mix fusion rules delivers optimal performance compared with most existing end-to-end fusion models.https://www.mdpi.com/2076-3417/13/23/12798multi-focus fusionmicroscope imagesSwin Transformer
spellingShingle Han Hank Xia
Hao Gao
Hang Shao
Kun Gao
Wei Liu
Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
Applied Sciences
multi-focus fusion
microscope images
Swin Transformer
title Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
title_full Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
title_fullStr Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
title_full_unstemmed Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
title_short Multi-Focus Microscopy Image Fusion Based on Swin Transformer Architecture
title_sort multi focus microscopy image fusion based on swin transformer architecture
topic multi-focus fusion
microscope images
Swin Transformer
url https://www.mdpi.com/2076-3417/13/23/12798
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AT haogao multifocusmicroscopyimagefusionbasedonswintransformerarchitecture
AT hangshao multifocusmicroscopyimagefusionbasedonswintransformerarchitecture
AT kungao multifocusmicroscopyimagefusionbasedonswintransformerarchitecture
AT weiliu multifocusmicroscopyimagefusionbasedonswintransformerarchitecture