Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.
The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. The lectin pathway is one pathway of three by which the complement system is activated. The characteristic protease of this pathway is Mannan-binding lectin (MBL)-associated serine pr...
Main Authors: | Anders Krarup, Russell Wallis, Julia S Presanis, Péter Gál, Robert B Sim |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1910608?pdf=render |
Similar Items
-
Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer
by: UP Fisch, et al.
Published: (2011-04-01) -
Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes
by: Mischa P. Keizer, et al.
Published: (2018-06-01) -
Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2.
by: Vorup-Jensen, T, et al.
Published: (2000) -
Critical role of lectin pathway mediated by MBL-associated serine proteases in complement activation for the pathogenesis in systemic lupus erythematosus
by: Yuko Asanuma, et al.
Published: (2023-08-01) -
Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1.
by: József Dobó, et al.
Published: (2011-01-01)