Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani
Standard INACS, Index of N-actyl-L-aspartate at centrum semiovale obtained by H- MRS, are compared to those of two Groups of volunteers. Group 1 was formed by 30 individuals (65-74 years old) with small cognition deficit probably due to early AD (Alzheimer’s Disease). Mean INACS of Group 1 was l...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Accademia Peloritana dei Pericolanti
2004-01-01
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| Series: | Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali |
| Online Access: | http://dx.doi.org/10.1478/c1a0401010 |
| _version_ | 1811248366837825536 |
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| author | Bramanti, P Bruschetta, P Rotondo, E Di Pasquale, MR |
| author_facet | Bramanti, P Bruschetta, P Rotondo, E Di Pasquale, MR |
| author_sort | Bramanti, P |
| collection | DOAJ |
| description | Standard INACS, Index of N-actyl-L-aspartate at centrum semiovale obtained by H- MRS, are compared to those of two Groups of volunteers. Group 1 was formed by 30 individuals (65-74 years old) with small cognition deficit probably due to early AD (Alzheimer’s Disease). Mean INACS of Group 1 was lower than the standard (significance = 89,4%, t = 1.64). This suggest that INACS evaluation could help early AD diagnosis. Group 2 was formed by 15 individuals (45-59 years old) with structural damages due to outcomes of Transitory Ischemic Attacks (TIA) or Minor Strokes (MS). In spite of the evident neuronal/axonal degeneration, mean INACS of this Group do not show significative decrease. This could be interpreted on the basis of the presence in the glial cell of N-acetyl derivatives whose resonances overlap the N-acetyl-L-aspartate one masking its lack. |
| first_indexed | 2024-04-12T15:25:43Z |
| format | Article |
| id | doaj.art-3c414cb73b5c4a04ac39f2a9a1e8886d |
| institution | Directory Open Access Journal |
| issn | 0365-0359 1825-1242 |
| language | English |
| last_indexed | 2024-04-12T15:25:43Z |
| publishDate | 2004-01-01 |
| publisher | Accademia Peloritana dei Pericolanti |
| record_format | Article |
| series | Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali |
| spelling | doaj.art-3c414cb73b5c4a04ac39f2a9a1e8886d2022-12-22T03:27:15ZengAccademia Peloritana dei PericolantiAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali0365-03591825-12422004-01-01LXXXI-LXXXII1c1a040101010.1478/c1a0401010Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umaniBramanti, PBruschetta, PRotondo, EDi Pasquale, MRStandard INACS, Index of N-actyl-L-aspartate at centrum semiovale obtained by H- MRS, are compared to those of two Groups of volunteers. Group 1 was formed by 30 individuals (65-74 years old) with small cognition deficit probably due to early AD (Alzheimer’s Disease). Mean INACS of Group 1 was lower than the standard (significance = 89,4%, t = 1.64). This suggest that INACS evaluation could help early AD diagnosis. Group 2 was formed by 15 individuals (45-59 years old) with structural damages due to outcomes of Transitory Ischemic Attacks (TIA) or Minor Strokes (MS). In spite of the evident neuronal/axonal degeneration, mean INACS of this Group do not show significative decrease. This could be interpreted on the basis of the presence in the glial cell of N-acetyl derivatives whose resonances overlap the N-acetyl-L-aspartate one masking its lack.http://dx.doi.org/10.1478/c1a0401010 |
| spellingShingle | Bramanti, P Bruschetta, P Rotondo, E Di Pasquale, MR Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali |
| title | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| title_full | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| title_fullStr | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| title_full_unstemmed | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| title_short | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| title_sort | studio comparativo h mrs di indici di n acetilaspartato ai centri semiovali umani |
| url | http://dx.doi.org/10.1478/c1a0401010 |
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