Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis
Background: we aim to investigate attitudes toward vaccination by analyzing empirical factors associated with vaccine acceptance in the Lazio region mpox vaccination (MpoxVax) campaign in Italy. Methods: all subjects who accessed MpoxVax and signed the informed consent were prospectively enrolled in...
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| Format: | Article |
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MDPI AG
2023-11-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/11/12/1761 |
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| author | Giulia Del Duca Alessandro Tavelli Ilaria Mastrorosa Camilla Aguglia Simone Lanini Anna Clelia Brita Roberta Gagliardini Serena Vita Alessandra Vergori Jessica Paulicelli Giorgia Natalini Angela D’Urso Pierluca Piselli Paola Gallì Vanessa Mondillo Claudio Mastroianni Enrica Tamburrini Loredana Sarmati Christof Stingone Miriam Lichtner Emanuele Nicastri Massimo Farinella Filippo Leserri Andrea Siddu Fabrizio Maggi Antonella d’Arminio Monforte Francesco Vairo Alessandra Barca Francesco Vaia Enrico Girardi Valentina Mazzotta Andrea Antinori |
| author_facet | Giulia Del Duca Alessandro Tavelli Ilaria Mastrorosa Camilla Aguglia Simone Lanini Anna Clelia Brita Roberta Gagliardini Serena Vita Alessandra Vergori Jessica Paulicelli Giorgia Natalini Angela D’Urso Pierluca Piselli Paola Gallì Vanessa Mondillo Claudio Mastroianni Enrica Tamburrini Loredana Sarmati Christof Stingone Miriam Lichtner Emanuele Nicastri Massimo Farinella Filippo Leserri Andrea Siddu Fabrizio Maggi Antonella d’Arminio Monforte Francesco Vairo Alessandra Barca Francesco Vaia Enrico Girardi Valentina Mazzotta Andrea Antinori |
| author_sort | Giulia Del Duca |
| collection | DOAJ |
| description | Background: we aim to investigate attitudes toward vaccination by analyzing empirical factors associated with vaccine acceptance in the Lazio region mpox vaccination (MpoxVax) campaign in Italy. Methods: all subjects who accessed MpoxVax and signed the informed consent were prospectively enrolled in the MPOX-VAC Study and were asked to fill out an anonymous survey. Two endpoints were selected: ‘delayed acceptance’ and ‘early acceptance’, defined as access for vaccination >60 and ≤30 days from the vaccination campaign starting (VCS), respectively. Results: over the study period, 1717 individuals underwent vaccination: 129 (7%) > 60 [1588 (92.5%) ≤ 60] and 676 (60%) ≤ 30 days from VCS. A bisexual orientation, a lower education level and a worse perceived physical and mental health were associated with delayed access to vaccination. Being pre-exposure prophylaxis (PrEP) users and, marginally, HIV positive; having a high perceived risk for mpox infection; and reporting high-risk behaviors like the use of recreational drugs/chems, sex under the influence of drugs and/or alcohol and having a higher number of principal sexual partners, were associated with early access to vaccination. Conclusions: according to our data, risk awareness was a major determinant of early MpoxVax acceptance. Conversely, worse perceived health status and a low educational level were critical factors associated with delayed vaccination. |
| first_indexed | 2024-03-08T20:17:58Z |
| format | Article |
| id | doaj.art-3c4210a3b212446c9fcb380abf783c8c |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-04-24T19:24:03Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-3c4210a3b212446c9fcb380abf783c8c2024-03-25T15:57:51ZengMDPI AGVaccines2076-393X2023-11-011112176110.3390/vaccines11121761Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional AnalysisGiulia Del Duca0Alessandro Tavelli1Ilaria Mastrorosa2Camilla Aguglia3Simone Lanini4Anna Clelia Brita5Roberta Gagliardini6Serena Vita7Alessandra Vergori8Jessica Paulicelli9Giorgia Natalini10Angela D’Urso11Pierluca Piselli12Paola Gallì13Vanessa Mondillo14Claudio Mastroianni15Enrica Tamburrini16Loredana Sarmati17Christof Stingone18Miriam Lichtner19Emanuele Nicastri20Massimo Farinella21Filippo Leserri22Andrea Siddu23Fabrizio Maggi24Antonella d’Arminio Monforte25Francesco Vairo26Alessandra Barca27Francesco Vaia28Enrico Girardi29Valentina Mazzotta30Andrea Antinori31Clinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyIcona Foundation, 20142 Milan, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyDepartment of Epidemiology, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyHealth Direction, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyHealth Direction, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University, AOU Policlinico Umberto 1, 00161 Rome, ItalyFondazione Policlinico A. Gemelli, Catholic University of the Sacred Heart, 00168 Rome, ItalyDepartment of System Medicine, University of Rome Tor Vergata, 00133 Rome, ItalySTI/HIV Unit, San Gallicano IRCCS Dermatological Institute, 00144 Rome, ItalyNeuroscience Mental Health and Sense Organs Department, Sapienza University of Rome, Polo Pontino, 04100 Latina, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyCircolo di Cultura Omosessuale Mario Mieli, 00146 Rome, ItalyPlus Roma, 00182 Rome, ItalyGeneral Directorate of Prevention, Ministry of Health, 00197 Rome, ItalyLaboratory of Virology, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyIcona Foundation, 20142 Milan, ItalyDepartment of Epidemiology, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyUnit of Health Promotion and Prevention, Directorate of Health and Integration, Lazio Region, 00145 Rome, ItalyGeneral Directorate of Prevention, Ministry of Health, 00197 Rome, ItalyScientific Direction, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyClinical Infectious Diseases Department, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, 00149 Rome, ItalyBackground: we aim to investigate attitudes toward vaccination by analyzing empirical factors associated with vaccine acceptance in the Lazio region mpox vaccination (MpoxVax) campaign in Italy. Methods: all subjects who accessed MpoxVax and signed the informed consent were prospectively enrolled in the MPOX-VAC Study and were asked to fill out an anonymous survey. Two endpoints were selected: ‘delayed acceptance’ and ‘early acceptance’, defined as access for vaccination >60 and ≤30 days from the vaccination campaign starting (VCS), respectively. Results: over the study period, 1717 individuals underwent vaccination: 129 (7%) > 60 [1588 (92.5%) ≤ 60] and 676 (60%) ≤ 30 days from VCS. A bisexual orientation, a lower education level and a worse perceived physical and mental health were associated with delayed access to vaccination. Being pre-exposure prophylaxis (PrEP) users and, marginally, HIV positive; having a high perceived risk for mpox infection; and reporting high-risk behaviors like the use of recreational drugs/chems, sex under the influence of drugs and/or alcohol and having a higher number of principal sexual partners, were associated with early access to vaccination. Conclusions: according to our data, risk awareness was a major determinant of early MpoxVax acceptance. Conversely, worse perceived health status and a low educational level were critical factors associated with delayed vaccination.https://www.mdpi.com/2076-393X/11/12/1761mpox infectionmpox vaccinationrisk awarenessvaccine acceptancevaccine hesitancyhealth-related quality of life |
| spellingShingle | Giulia Del Duca Alessandro Tavelli Ilaria Mastrorosa Camilla Aguglia Simone Lanini Anna Clelia Brita Roberta Gagliardini Serena Vita Alessandra Vergori Jessica Paulicelli Giorgia Natalini Angela D’Urso Pierluca Piselli Paola Gallì Vanessa Mondillo Claudio Mastroianni Enrica Tamburrini Loredana Sarmati Christof Stingone Miriam Lichtner Emanuele Nicastri Massimo Farinella Filippo Leserri Andrea Siddu Fabrizio Maggi Antonella d’Arminio Monforte Francesco Vairo Alessandra Barca Francesco Vaia Enrico Girardi Valentina Mazzotta Andrea Antinori Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis Vaccines mpox infection mpox vaccination risk awareness vaccine acceptance vaccine hesitancy health-related quality of life |
| title | Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis |
| title_full | Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis |
| title_fullStr | Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis |
| title_full_unstemmed | Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis |
| title_short | Risk Awareness as a Key Determinant of Early Vaccine Uptake in the Mpox Vaccination Campaign in an Italian Region: A Cross-Sectional Analysis |
| title_sort | risk awareness as a key determinant of early vaccine uptake in the mpox vaccination campaign in an italian region a cross sectional analysis |
| topic | mpox infection mpox vaccination risk awareness vaccine acceptance vaccine hesitancy health-related quality of life |
| url | https://www.mdpi.com/2076-393X/11/12/1761 |
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