Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)

Background: The aim of this investigation is to evaluate the histologic results of biopsy in women with atypical squamous cells of undetermined significance (ASCUS) cytologic diagnosis. Materials and Methods: We reviewed a series of cases with ASCUS pap smears from March 1999 to Feb 2002 in Imam Kho...

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Main Authors: Ghaem Maghami F, Ensani F, Behtash N, Hosseini Nejad S E
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2004-09-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/972.pdf&manuscript_id=972
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author Ghaem Maghami F
Ensani F
Behtash N
Hosseini Nejad S E
author_facet Ghaem Maghami F
Ensani F
Behtash N
Hosseini Nejad S E
author_sort Ghaem Maghami F
collection DOAJ
description Background: The aim of this investigation is to evaluate the histologic results of biopsy in women with atypical squamous cells of undetermined significance (ASCUS) cytologic diagnosis. Materials and Methods: We reviewed a series of cases with ASCUS pap smears from March 1999 to Feb 2002 in Imam Khomeini Hospital (n= 104), Who had cervical biopsy indirected colposcopy (103) and in Onec endocervical biopsy obtained without colposcopy. In 60 patients before colposcopy and biopsy repeat pap smear was tabled. Results: Biopsy revealed 28.8% SIL (14 LSIL and 16 HSIL), 1 invasive carcinoma and 1 endometrial carcinoma. Pap smear repeated for 60 women before colposcopy examination, which 7 (11.7%) of them were normal. ASCUS persisted in 45 cases (75%) and 8 cases (13.3%) turned out to be SIL (6 LSIL, 2 HSIL) of 7 normal repeat smear, 2 marked as LSIL by biopsy. In colposcopic examination 22 of 103 (21.4%) had normal view which one of them was LSIL histologically. Conclusion: Based on these findings, it seems immediate colposcopy and directed biopsy are appropriate procedures for management of ASCUS and to detect underlying SIL.
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spelling doaj.art-3c450be60a4b417ba20ef2e0420cabb32022-12-21T19:51:35ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222004-09-01624326332Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)Ghaem Maghami FEnsani FBehtash NHosseini Nejad S EBackground: The aim of this investigation is to evaluate the histologic results of biopsy in women with atypical squamous cells of undetermined significance (ASCUS) cytologic diagnosis. Materials and Methods: We reviewed a series of cases with ASCUS pap smears from March 1999 to Feb 2002 in Imam Khomeini Hospital (n= 104), Who had cervical biopsy indirected colposcopy (103) and in Onec endocervical biopsy obtained without colposcopy. In 60 patients before colposcopy and biopsy repeat pap smear was tabled. Results: Biopsy revealed 28.8% SIL (14 LSIL and 16 HSIL), 1 invasive carcinoma and 1 endometrial carcinoma. Pap smear repeated for 60 women before colposcopy examination, which 7 (11.7%) of them were normal. ASCUS persisted in 45 cases (75%) and 8 cases (13.3%) turned out to be SIL (6 LSIL, 2 HSIL) of 7 normal repeat smear, 2 marked as LSIL by biopsy. In colposcopic examination 22 of 103 (21.4%) had normal view which one of them was LSIL histologically. Conclusion: Based on these findings, it seems immediate colposcopy and directed biopsy are appropriate procedures for management of ASCUS and to detect underlying SIL.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/972.pdf&manuscript_id=972pap smearcervical biopsySIL
spellingShingle Ghaem Maghami F
Ensani F
Behtash N
Hosseini Nejad S E
Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
Tehran University Medical Journal
pap smear
cervical biopsy
SIL
title Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
title_full Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
title_fullStr Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
title_full_unstemmed Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
title_short Histologic Findings Of Uterine Cervix Among Women With Cytologic Diagnosis Of ASCUS (Atypical Squamous Cells Of Undetermined Significance)
title_sort histologic findings of uterine cervix among women with cytologic diagnosis of ascus atypical squamous cells of undetermined significance
topic pap smear
cervical biopsy
SIL
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/972.pdf&manuscript_id=972
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AT ensanif histologicfindingsofuterinecervixamongwomenwithcytologicdiagnosisofascusatypicalsquamouscellsofundeterminedsignificance
AT behtashn histologicfindingsofuterinecervixamongwomenwithcytologicdiagnosisofascusatypicalsquamouscellsofundeterminedsignificance
AT hosseininejadse histologicfindingsofuterinecervixamongwomenwithcytologicdiagnosisofascusatypicalsquamouscellsofundeterminedsignificance