Gut Microbiota and Metabolic Disorders
Gut microbiota plays critical physiological roles in the energy extraction and in the control of local or systemic immunity. Gut microbiota and its disturbance also appear to be involved in the pathogenesis of diverse diseases including metabolic disorders, gastrointestinal diseases, cancer, etc. In...
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Format: | Article |
Language: | English |
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Korean Diabetes Association
2015-06-01
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Series: | Diabetes & Metabolism Journal |
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Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-198.pdf |
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author | Kyu Yeon Hur Myung-Shik Lee |
author_facet | Kyu Yeon Hur Myung-Shik Lee |
author_sort | Kyu Yeon Hur |
collection | DOAJ |
description | Gut microbiota plays critical physiological roles in the energy extraction and in the control of local or systemic immunity. Gut microbiota and its disturbance also appear to be involved in the pathogenesis of diverse diseases including metabolic disorders, gastrointestinal diseases, cancer, etc. In the metabolic point of view, gut microbiota can modulate lipid accumulation, lipopolysaccharide content and the production of short-chain fatty acids that affect food intake, inflammatory tone, or insulin signaling. Several strategies have been developed to change gut microbiota such as prebiotics, probiotics, certain antidiabetic drugs or fecal microbiota transplantation, which have diverse effects on body metabolism and on the development of metabolic disorders. |
first_indexed | 2024-12-20T04:17:21Z |
format | Article |
id | doaj.art-3c485b3934d8418aa69a32b7d6daa8ea |
institution | Directory Open Access Journal |
issn | 2233-6079 2233-6087 |
language | English |
last_indexed | 2024-12-20T04:17:21Z |
publishDate | 2015-06-01 |
publisher | Korean Diabetes Association |
record_format | Article |
series | Diabetes & Metabolism Journal |
spelling | doaj.art-3c485b3934d8418aa69a32b7d6daa8ea2022-12-21T19:53:43ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872015-06-0139319820310.4093/dmj.2015.39.3.19814680Gut Microbiota and Metabolic DisordersKyu Yeon HurMyung-Shik LeeGut microbiota plays critical physiological roles in the energy extraction and in the control of local or systemic immunity. Gut microbiota and its disturbance also appear to be involved in the pathogenesis of diverse diseases including metabolic disorders, gastrointestinal diseases, cancer, etc. In the metabolic point of view, gut microbiota can modulate lipid accumulation, lipopolysaccharide content and the production of short-chain fatty acids that affect food intake, inflammatory tone, or insulin signaling. Several strategies have been developed to change gut microbiota such as prebiotics, probiotics, certain antidiabetic drugs or fecal microbiota transplantation, which have diverse effects on body metabolism and on the development of metabolic disorders.http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-198.pdfGutMetforminMicrobiotaObesity |
spellingShingle | Kyu Yeon Hur Myung-Shik Lee Gut Microbiota and Metabolic Disorders Diabetes & Metabolism Journal Gut Metformin Microbiota Obesity |
title | Gut Microbiota and Metabolic Disorders |
title_full | Gut Microbiota and Metabolic Disorders |
title_fullStr | Gut Microbiota and Metabolic Disorders |
title_full_unstemmed | Gut Microbiota and Metabolic Disorders |
title_short | Gut Microbiota and Metabolic Disorders |
title_sort | gut microbiota and metabolic disorders |
topic | Gut Metformin Microbiota Obesity |
url | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-198.pdf |
work_keys_str_mv | AT kyuyeonhur gutmicrobiotaandmetabolicdisorders AT myungshiklee gutmicrobiotaandmetabolicdisorders |