DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease

DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease

DNA repair ensures genomic stability to achieve healthy ageing, including cognitive maintenance. Mutations on genes encoding key DNA repair proteins can lead to diseases with accelerated ageing phenotypes. Some of these diseases are xeroderma pigmentosum group A (XPA, caused by mutation of <i>...

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Bibliographic Details
Main Authors: Heling Wang, Sofie Lautrup, Domenica Caponio, Jianying Zhang, Evandro F. Fang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage
DNA repair
Alzheimer’s disease (AD)
age-related disease
Online Access:https://www.mdpi.com/1422-0067/22/13/6748

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