Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study
Abstract Background COPD combined with respiratory failure is very common in intensive care unit (ICU). We aimed to evaluate the current status and influencing factors of delirium in elderly COPD patients with undergoing mechanical ventilation. Methods Patients with COPD combined with respiratory fa...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-022-02052-5 |
| _version_ | 1811219279442345984 |
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| author | Xuecai Fu Lina Wang Guihua Wang Xuefang Liu Xin Wang Shuiting Ma Fengru Miao |
| author_facet | Xuecai Fu Lina Wang Guihua Wang Xuefang Liu Xin Wang Shuiting Ma Fengru Miao |
| author_sort | Xuecai Fu |
| collection | DOAJ |
| description | Abstract Background COPD combined with respiratory failure is very common in intensive care unit (ICU). We aimed to evaluate the current status and influencing factors of delirium in elderly COPD patients with undergoing mechanical ventilation. Methods Patients with COPD combined with respiratory failure and mechanically ventilated who were admitted to the ICU of our hospital were selected. The characteristics of included patients were assessed. Pearson correlation analysis was performed to evaluate the characteristics of patients and delirium. Logistic regression analysis was conducted to identify the risk factors of delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation. Results A total of 237 COPD combined with respiratory failure patients were included, the incidence of delirium was 21.94%. Pearson correlation analysis indicated that age (r = 0.784), BMI (r = 0.709), hypertension (r = 0.696), APACHE II score (r = 0.801), CPOT (r = 0.513), sedation(r = 0.626) and PaO2 (r = 0.611) were all correlated with the occurrence of delirium (all p < 0.05). Logistic regression analysis indicated that age ≥ 75y (OR 3.112, 95% CI 2.144–4.602), BMI ≤ 19 kg/m2 (OR 2.742, 95% CI 1.801–3.355), hypertension(OR 1.909, 95% CI 1.415–2.421), APACHE II score ≥ 15 (OR 2.087, 95% CI 1.724–2.615), CPOT ≥ 5 (OR 1.778, 95% CI 1.206–2.641), sedation(OR 3.147, 95% CI 2.714–3.758), PaO2 ≤ 75 mmHg(OR 2.196, 95%CI 1.875–3.088) were the risk factors of delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation (all p < 0.05). Conclusions Delirium is common in patients with COPD and respiratory failure undergoing mechanical ventilation, and there are many related influencing factors. Medical staff should pay more attention to patients with risk factors and take intervention measures as soon as possible to reduce the incidence of delirium. |
| first_indexed | 2024-04-12T07:24:48Z |
| format | Article |
| id | doaj.art-3c4c81794efc4647812dba7f274e208a |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-04-12T07:24:48Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-3c4c81794efc4647812dba7f274e208a2022-12-22T03:42:14ZengBMCBMC Pulmonary Medicine1471-24662022-07-012211810.1186/s12890-022-02052-5Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort studyXuecai Fu0Lina Wang1Guihua Wang2Xuefang Liu3Xin Wang4Shuiting Ma5Fengru Miao6Geriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalGeriatrics Department, Aerospace Center HospitalAbstract Background COPD combined with respiratory failure is very common in intensive care unit (ICU). We aimed to evaluate the current status and influencing factors of delirium in elderly COPD patients with undergoing mechanical ventilation. Methods Patients with COPD combined with respiratory failure and mechanically ventilated who were admitted to the ICU of our hospital were selected. The characteristics of included patients were assessed. Pearson correlation analysis was performed to evaluate the characteristics of patients and delirium. Logistic regression analysis was conducted to identify the risk factors of delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation. Results A total of 237 COPD combined with respiratory failure patients were included, the incidence of delirium was 21.94%. Pearson correlation analysis indicated that age (r = 0.784), BMI (r = 0.709), hypertension (r = 0.696), APACHE II score (r = 0.801), CPOT (r = 0.513), sedation(r = 0.626) and PaO2 (r = 0.611) were all correlated with the occurrence of delirium (all p < 0.05). Logistic regression analysis indicated that age ≥ 75y (OR 3.112, 95% CI 2.144–4.602), BMI ≤ 19 kg/m2 (OR 2.742, 95% CI 1.801–3.355), hypertension(OR 1.909, 95% CI 1.415–2.421), APACHE II score ≥ 15 (OR 2.087, 95% CI 1.724–2.615), CPOT ≥ 5 (OR 1.778, 95% CI 1.206–2.641), sedation(OR 3.147, 95% CI 2.714–3.758), PaO2 ≤ 75 mmHg(OR 2.196, 95%CI 1.875–3.088) were the risk factors of delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation (all p < 0.05). Conclusions Delirium is common in patients with COPD and respiratory failure undergoing mechanical ventilation, and there are many related influencing factors. Medical staff should pay more attention to patients with risk factors and take intervention measures as soon as possible to reduce the incidence of delirium.https://doi.org/10.1186/s12890-022-02052-5COPDRespiratory failureMechanical ventilationElderDeliriumCare |
| spellingShingle | Xuecai Fu Lina Wang Guihua Wang Xuefang Liu Xin Wang Shuiting Ma Fengru Miao Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study BMC Pulmonary Medicine COPD Respiratory failure Mechanical ventilation Elder Delirium Care |
| title | Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study |
| title_full | Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study |
| title_fullStr | Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study |
| title_full_unstemmed | Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study |
| title_short | Delirium in elderly patients with COPD combined with respiratory failure undergoing mechanical ventilation: a prospective cohort study |
| title_sort | delirium in elderly patients with copd combined with respiratory failure undergoing mechanical ventilation a prospective cohort study |
| topic | COPD Respiratory failure Mechanical ventilation Elder Delirium Care |
| url | https://doi.org/10.1186/s12890-022-02052-5 |
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