Staurosporine Induces Filamentation in the Human Fungal Pathogen <named-content content-type="genus-species">Candida albicans</named-content> via Signaling through Cyr1 and Protein Kinase A

Staurosporine Induces Filamentation in the Human Fungal Pathogen <named-content content-type="genus-species">Candida albicans</named-content> via Signaling through Cyr1 and Protein Kinase A

ABSTRACT Protein kinases are key regulators of signal transduction pathways that participate in diverse cellular processes. In fungal pathogens, kinases regulate signaling pathways that govern drug resistance, stress adaptation, and pathogenesis. The impact of kinases on the fungal regulatory circui...

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Bibliographic Details
Main Authors: Jinglin L. Xie, Teresa R. O’Meara, Elizabeth J. Polvi, Nicole Robbins, Leah E. Cowen
Format: Article
Language:English
Published: American Society for Microbiology 2017-04-01
Series:mSphere
Subjects:
Candida albicans
cyclic AMP
kinase inhibitor
morphogenesis
staurosporine
virulence
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00056-17

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