Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium
A novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(I...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-01-01
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| Series: | Food and Agricultural Immunology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09540105.2017.1354358 |
| _version_ | 1818341933127303168 |
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| author | Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang |
| author_facet | Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang |
| author_sort | Shanshan Song |
| collection | DOAJ |
| description | A novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(II)–1-(4-isothiocyanobenzyl) ethylenediamine-N,N,N′,N′-tetraacetic acid (EDTA) (Cd(II)–ITCBE) and not metal-free ITCBE and EDTA. The cutoff value for semi-quantitative detection of the strip was 5 ng/mL and the lower limit of detection for quantitative detection was 0.2 ng/mL using a scanning reader. The percent recovery ranged from 107.6% to 132% in tap water samples. |
| first_indexed | 2024-12-13T16:06:40Z |
| format | Article |
| id | doaj.art-3c51fc5cf87b4d378d3a89581d87e974 |
| institution | Directory Open Access Journal |
| issn | 0954-0105 1465-3443 |
| language | English |
| last_indexed | 2024-12-13T16:06:40Z |
| publishDate | 2018-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Food and Agricultural Immunology |
| spelling | doaj.art-3c51fc5cf87b4d378d3a89581d87e9742022-12-21T23:39:02ZengTaylor & Francis GroupFood and Agricultural Immunology0954-01051465-34432018-01-0129131310.1080/09540105.2017.13543581354358Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmiumShanshan Song0Shuzhen Zou1Jianping Zhu2Liqiang Liu3Hua Kuang4State Key Laboratory of Food Science and Technology, Jiangnan UniversityState Key Laboratory of Food Science and Technology, Jiangnan UniversityState Key Laboratory of Food Science and Technology, Jiangnan UniversityState Key Laboratory of Food Science and Technology, Jiangnan UniversityState Key Laboratory of Food Science and Technology, Jiangnan UniversityA novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(II)–1-(4-isothiocyanobenzyl) ethylenediamine-N,N,N′,N′-tetraacetic acid (EDTA) (Cd(II)–ITCBE) and not metal-free ITCBE and EDTA. The cutoff value for semi-quantitative detection of the strip was 5 ng/mL and the lower limit of detection for quantitative detection was 0.2 ng/mL using a scanning reader. The percent recovery ranged from 107.6% to 132% in tap water samples.http://dx.doi.org/10.1080/09540105.2017.1354358cadmiumimmunochromatographic stripmonoclonal antibodygold-nanoparticle (gnp) |
| spellingShingle | Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium Food and Agricultural Immunology cadmium immunochromatographic strip monoclonal antibody gold-nanoparticle (gnp) |
| title | Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| title_full | Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| title_fullStr | Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| title_full_unstemmed | Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| title_short | Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| title_sort | immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
| topic | cadmium immunochromatographic strip monoclonal antibody gold-nanoparticle (gnp) |
| url | http://dx.doi.org/10.1080/09540105.2017.1354358 |
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