Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis.

Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis.

We previously reported that Candida albicans cell surface protein Hyr1 encodes a phagocyte killing resistance factor and active vaccination with a recombinant N-terminus of Hyr1 protein (rHyr1p-N), significantly protects immunocompetent mice from disseminated candidiasis. Here we report the marked e...

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Bibliographic Details
Main Authors: Guanpingsheng Luo, Ashraf S Ibrahim, Samuel W French, John E Edwards, Yue Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3189951?pdf=render

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