Hypoglycemic and Anti-Inflammatory Effects of Triterpene Glycoside Fractions from <i>Aeculus hippocastanum</i> Seeds

Hypoglycemic and Anti-Inflammatory Effects of Triterpene Glycoside Fractions from <i>Aeculus hippocastanum</i> Seeds

Horse chestnut (<i>Aesculus hippocastanum</i> L.)-derived drugs have shown their potential in biomedical applications. The seed of <i>A. hippocastanum</i> contains various kinds of chemical compounds including phenolics, flavonoids, coumarins, and triterpene saponins. Here, w...

Full description

Bibliographic Details
Main Authors:	Avez Sharipov, Khurshid Tursunov, Sunnatullo Fazliev, Bahtigul Azimova, Jamoliddin Razzokov
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Molecules
Subjects:	chestnut saponin escin biological activity diabetes inflammation
Online Access:	https://www.mdpi.com/1420-3049/26/13/3784

Similar Items

Escin’s Multifaceted Therapeutic Profile in Treatment and Post-Treatment of Various Cancers: A Comprehensive Review
by: Sunnatullo Fazliev, et al.
Published: (2023-02-01)

Effect of Cholesterol and Ibuprofen on DMPC-<i>β</i>-Aescin Bicelles: A Temperature-Dependent Wide-Angle X-ray Scattering Study
by: Ramsia Geisler, et al.
Published: (2020-05-01)

Development of an Improved Method for the Determination of Iodine/β-Cyclodextrin by Means of HPLC-UV: Validation and the Thyroid-Stimulating Activity Revealed by In Vivo Studies
by: Avez Sharipov, et al.
Published: (2021-06-01)

Benefits of Escin for Decompression Sickness in Bama Pigs by Endothelial-Targeting Protection
by: Long Qing, et al.
Published: (2019-05-01)

Corrigendum: Benefits of Escin for Decompression Sickness in Bama Pigs by Endothelial-Targeting Protection
by: Long Qing, et al.
Published: (2019-06-01)

Quality and Technological Properties of Flour with the Addition of Aesculus Hippocastanum and Castanea Sativa
by: Sikora Fryderyk, et al.
Published: (2022-06-01)

Comparative Analysis of Quality Requirements for Medicines Based on Horse-Chestnut Seeds
by: O. V. Evdokimova, et al.
Published: (2023-09-01)

Triterpenes and triterpenoidal glycosides from the fruits of Ilex paraguariensis (Maté)
by: Taketa Alexandre T. C., et al.
Published: (2004-01-01)

The Influence of Urban Conditions on the Phenology of <i>Aesculus hippocastanum</i> L. Using the Example of Wroclaw (Poland)
by: Iwona Dominika Orzechowska-Szajda, et al.
Published: (2020-11-01)

Phenolic-Based Discrimination between Non-Symptomatic and Symptomatic Leaves of <i>Aesculus hippocastanum</i> Infested by <i>Cameraria ohridella</i> and <i>Erysiphe flexuosa</i>
by: Agnieszka Hanaka, et al.
Published: (2023-09-01)

Analytical Concentrations of Some Elements in Seeds and Crude Extracts from <i>Aesculus hippocastanum</i>, by ICP-OES Technique
by: Caterina Durante, et al.
Published: (2020-12-01)

Is it justifiable to assert that clinical lycanthropy may be correlated to porphyria cutanea tarda?
by: Lorenzo Martini
Published: (2017-10-01)

Potential Activity Mechanisms of <i>Aesculus hippocastanum</i> Bark: Antioxidant Effects in Chemical and Biological In Vitro Models
by: Aleksandra Owczarek, et al.
Published: (2021-06-01)

Novel Oxime-Derivatized Synthetic Triterpene Glycosides as Potent Saponin Vaccine Adjuvants
by: Roberto Fuentes, et al.
Published: (2022-05-01)

THE PESTS OF HORSE CHESTNUT TREE – AESCULUS HIPPOCASTANUM L. IN ROMANIA
by: T PERJU, et al.
Published: (2005-04-01)

<i>Aesculus hippocastanum</i> L.: A Simple Ornamental Plant or a Source of Compelling Molecules for Industry?
by: Asma Dridi, et al.
Published: (2023-02-01)

The Occurrence of some Lepidopterous species on the horse chestnut (Aesculus hippocastanum L.) at Istanbul-Belgrad Forest in Turkey
by: H. Huseyin CEBECI, et al.
Published: (2007-08-01)

<i>Aesculus hippocastanum</i> L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats
by: Ivan Kováč, et al.
Published: (2020-04-01)

Species Composition and Seasonal Abundance of Predatory Mites (Acari: Phytoseiidae) Inhabiting <i>Aesculus hippocastanum</i> (Sapindaceae)
by: Michal Kopačka, et al.
Published: (2023-05-01)

Isomadecassoside, a New Ursane-Type Triterpene Glycoside from <i>Centella asiatica</i> Leaves, Reduces Nitrite Levels in LPS-Stimulated Macrophages
by: Giuseppina Chianese, et al.
Published: (2021-03-01)

<i>Brenneria nigrifluens</i> Isolated from <i>Aesculus hippocastanum</i> L. Bark in Hungary
by: Imola Tenorio-Baigorria, et al.
Published: (2022-02-01)

Effect of Sun Exposure of the Horse Chestnut (<i>Aesculus hippocastanum</i> L.) on the Occurrence and Number of <i>Cameraria ohridella</i> (Lepidoptera: Gracillariidae)
by: Liliya R. Bogoutdinova, et al.
Published: (2023-05-01)

Preparation of selectively protected protoescigenin derivatives for synthesis of escin analogs and neoglycoconjugates
by: Jatczak Kamil, et al.
Published: (2014-12-01)

Description of Intra-Annual Changes in Cambial Activity and Differentiation of Secondary Conductive Tissues of <i>Aesculus hippocastanum</i> Trees Affected by the Leaf Miner <i>Cameraria ohridella</i>
by: Elżbieta Myśkow, et al.
Published: (2021-11-01)

<i>Aesculus hippocastanum</i> L. as a Stabilizer in Hemp Seed Oil Nanoemulsions for Potential Biomedical and Food Applications
by: Maciej Jarzębski, et al.
Published: (2021-01-01)

Investigation of Costus : V. Triterpenes of Costus speciosus roots /
by: 223915 Gupta, M. M.

Effect of Cameraria ohridella on accumulation of proteins, peroxidase activity and composition in Aesculus hippocastanum leaves
by: O. V. Seliutina, et al.
Published: (2020-04-01)

Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione, and Escin on Human Health: A Narrative Review
by: Francesco Sebastiani, et al.
Published: (2023-08-01)

Combination treatment for acute non-specific low back pain
by: A. E. Barulin, et al.
Published: (2014-10-01)

TLC-densitometric analysis of α-escin in bulk drug substance and in pharmaceutical dosage forms
by: Dolowy Malgorzata, et al.
Published: (2015-09-01)

Effect of Electric Field on α-Synuclein Fibrils: Revealed by Molecular Dynamics Simulations
by: Jamoliddin Razzokov, et al.
Published: (2023-03-01)

Horse Chestnut (Aesculus hippocastanum L.) Urban Habitat - Pollution Influence on Some Phenotypic and Morphological Characteristics
by: Fran Poštenjak, et al.
Published: (2012-12-01)

A Review of the Use of Chestnut in Traditional and Innovative Food Products
by: Raquel P. F. Guiné, et al.
Published: (2023-03-01)

Mechanistic Insight into Permeation of Plasma-Generated Species from Vacuum into Water Bulk
by: Jamoliddin Razzokov, et al.
Published: (2022-06-01)

Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis
by: Leiming Zhang, et al.
Published: (2019-03-01)

Triterpene saponins of Trigonella monspeliaca L.
by: Wiesław Oleszek, et al.
Published: (2014-01-01)

Evaluation of Topical Anti-Inflammatory Effects of a Gel Formulation with Plantago Lanceolata, Achillea Millefolium, Aesculus Hippocastanum and Taxodium Distichum
by: Anca Zanfirescu, et al.
Published: (2020-05-01)

Effect of Escin Alone or in Combination with Antifungal Agents on Resistant <i>Candida glabrata</i> Biofilms: Mechanisms of Action
by: Angela Maione, et al.
Published: (2023-07-01)

Climate Change Projections for Bioclimatic Distribution of <i>Castanea sativa</i> in Portugal
by: Teresa R. Freitas, et al.
Published: (2022-05-01)

Qualidade de medicamentos fitoterápicos contendo extrato de Aesculus hippocastanum registrados no Brasil / Quality of phytotherapeutic drugs registered in Brazil containing Aesculus hippocastanum extract
by: Evelin Elfriede Balbino, et al.
Published: (2014-08-01)