Dysregulation of BET proteins in levodopa-induced dyskinesia

Dysregulation of BET proteins in levodopa-induced dyskinesia

Levodopa (L-DOPA) remains the most effective pharmacological treatment for Parkinson Disease (PD) but its use is limited by the development of debilitating drug-related side effects, particularly L-DOPA induced dyskinesia (LID). LID is a consequence of long-term L-DOPA use, and in model systems is c...

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Bibliographic Details
Main Authors: David A. Figge, David G. Standaert
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Neurobiology of Disease
Subjects:
BET proteins
JQ1
Dyskinesia
L-DOPA
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117300505

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