p53 immunostaining is correlated with reduced survival and is not correlated with gene mutations in resected pulmonary large cell carcinomas

p53 immunostaining is correlated with reduced survival and is not correlated with gene mutations in resected pulmonary large cell carcinomas

Malignancy of pulmonary large cell carcinomas (LCC) increases from classic LCC through LCC with neuroendocrine morphology (LCCNM) to large cell neuroendocrine carcinomas (LCNEC). However, the histological classification has sometimes proved to be difficult. Because the malignancy of LCC is highly de...

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Bibliographic Details
Main Authors: L.M. Massoni Neto, C.P. Bianchi, A.M. Ab'Saber, E.R. Parra, T. Takagaki, J.C. Pereira, F.A. Soares, K. Leite, V.L. Capelozzi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Large cell carcinoma
p53
Genetics
Molecular biology
Lung cancer
Mutation analysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800004

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