Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects

Molecular Cloning Designer Simulator (MCDS) is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects. In addition to standard functions, it has a number of features that...

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Main Authors: Zhenyu Shi, Claudia E. Vickers
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Metabolic Engineering Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030116300153
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author Zhenyu Shi
Claudia E. Vickers
author_facet Zhenyu Shi
Claudia E. Vickers
author_sort Zhenyu Shi
collection DOAJ
description Molecular Cloning Designer Simulator (MCDS) is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects. In addition to standard functions, it has a number of features that are either unique, or are not found in combination in any one software package: (1) it has a novel interactive flow-chart user interface for complex multi-step processes, allowing an integrated overview of the whole project; (2) it can perform a user-defined workflow of cloning steps in a single execution of the software; (3) it can handle multiple types of genetic recombineering, a technique that is rapidly replacing classical cloning for many applications; (4) it includes experimental information to conveniently guide wet lab work; and (5) it can store results and comments to allow the tracking and management of the whole project in one platform. MCDS is freely available from https://mcds.codeplex.com. Keywords: BioCAD, Genetic engineering software, Molecular cloning software, Synthetic biology, Workflow simulation and management
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spelling doaj.art-3c598a9ec2954429ad9d0cc775c402962022-12-21T18:56:52ZengElsevierMetabolic Engineering Communications2214-03012016-12-013173186Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projectsZhenyu Shi0Claudia E. Vickers1Corresponding author.; Australian Institute for Bioengineering & Nanotechnology, The University of Queensland, St Lucia, QLD 4072, AustraliaAustralian Institute for Bioengineering & Nanotechnology, The University of Queensland, St Lucia, QLD 4072, AustraliaMolecular Cloning Designer Simulator (MCDS) is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects. In addition to standard functions, it has a number of features that are either unique, or are not found in combination in any one software package: (1) it has a novel interactive flow-chart user interface for complex multi-step processes, allowing an integrated overview of the whole project; (2) it can perform a user-defined workflow of cloning steps in a single execution of the software; (3) it can handle multiple types of genetic recombineering, a technique that is rapidly replacing classical cloning for many applications; (4) it includes experimental information to conveniently guide wet lab work; and (5) it can store results and comments to allow the tracking and management of the whole project in one platform. MCDS is freely available from https://mcds.codeplex.com. Keywords: BioCAD, Genetic engineering software, Molecular cloning software, Synthetic biology, Workflow simulation and managementhttp://www.sciencedirect.com/science/article/pii/S2214030116300153
spellingShingle Zhenyu Shi
Claudia E. Vickers
Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
Metabolic Engineering Communications
title Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
title_full Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
title_fullStr Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
title_full_unstemmed Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
title_short Molecular Cloning Designer Simulator (MCDS): All-in-one molecular cloning and genetic engineering design, simulation and management software for complex synthetic biology and metabolic engineering projects
title_sort molecular cloning designer simulator mcds all in one molecular cloning and genetic engineering design simulation and management software for complex synthetic biology and metabolic engineering projects
url http://www.sciencedirect.com/science/article/pii/S2214030116300153
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AT claudiaevickers molecularcloningdesignersimulatormcdsallinonemolecularcloningandgeneticengineeringdesignsimulationandmanagementsoftwareforcomplexsyntheticbiologyandmetabolicengineeringprojects