Epidemiology of gout and chondrocalcinosis

Gout is the most common cause of inflammatory arthritis affecting at least 1% of the population in industrialized countries. It is closely associated with hyperuricemia and is characterized by formation and reversible deposition of monosodium urate crystals in joints and extra-articular tissues. Sev...

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Main Authors: M. Govoni, A. Bortoluzzi, G. Ciancio
Format: Article
Language:English
Published: PAGEPress Publications 2012-01-01
Series:Reumatismo
Subjects:
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/562
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author M. Govoni
A. Bortoluzzi
G. Ciancio
author_facet M. Govoni
A. Bortoluzzi
G. Ciancio
author_sort M. Govoni
collection DOAJ
description Gout is the most common cause of inflammatory arthritis affecting at least 1% of the population in industrialized countries. It is closely associated with hyperuricemia and is characterized by formation and reversible deposition of monosodium urate crystals in joints and extra-articular tissues. Several studies suggest that the prevalence and incidence of gout are rising. Numerous risk factors may in part explain this increasing trend including dietary and lifestyle changes, genetic factors, diuretic use and comorbid conditions such as hypertension, diabetes, cardiovascular disease, chronic renal disease and the metabolic syndrome. Chondrocalcinosis is characterized by the deposition of calcium pyrophosphate crystals in articular tissues, most commonly fibrocartilage and hyaline cartilage. Sporadic chondrocalcinosis is a common condition in the elderly and frequently associates with osteoarthritis. Hereditary haemochromatosis, hyperparathyroidism and hypomagnesaemia are metabolic disorders that predispose to secondary chondrocalcinosis.The prevalence of chondrocalcinosis is still rather uncertain and varies depending on the diagnostic criterion used in different studies.
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spelling doaj.art-3c5a1ec28a024e1fb1e2fde75dafd5512022-12-22T01:11:15ZengPAGEPress PublicationsReumatismo0048-74492240-26832012-01-0163420722010.4081/reumatismo.2011.207Epidemiology of gout and chondrocalcinosisM. GovoniA. BortoluzziG. CiancioGout is the most common cause of inflammatory arthritis affecting at least 1% of the population in industrialized countries. It is closely associated with hyperuricemia and is characterized by formation and reversible deposition of monosodium urate crystals in joints and extra-articular tissues. Several studies suggest that the prevalence and incidence of gout are rising. Numerous risk factors may in part explain this increasing trend including dietary and lifestyle changes, genetic factors, diuretic use and comorbid conditions such as hypertension, diabetes, cardiovascular disease, chronic renal disease and the metabolic syndrome. Chondrocalcinosis is characterized by the deposition of calcium pyrophosphate crystals in articular tissues, most commonly fibrocartilage and hyaline cartilage. Sporadic chondrocalcinosis is a common condition in the elderly and frequently associates with osteoarthritis. Hereditary haemochromatosis, hyperparathyroidism and hypomagnesaemia are metabolic disorders that predispose to secondary chondrocalcinosis.The prevalence of chondrocalcinosis is still rather uncertain and varies depending on the diagnostic criterion used in different studies.http://www.reumatismo.org/index.php/reuma/article/view/562gout, CPPD, chondrocalcinosis, epidemiology, incidence, prevalence
spellingShingle M. Govoni
A. Bortoluzzi
G. Ciancio
Epidemiology of gout and chondrocalcinosis
Reumatismo
gout, CPPD, chondrocalcinosis, epidemiology, incidence, prevalence
title Epidemiology of gout and chondrocalcinosis
title_full Epidemiology of gout and chondrocalcinosis
title_fullStr Epidemiology of gout and chondrocalcinosis
title_full_unstemmed Epidemiology of gout and chondrocalcinosis
title_short Epidemiology of gout and chondrocalcinosis
title_sort epidemiology of gout and chondrocalcinosis
topic gout, CPPD, chondrocalcinosis, epidemiology, incidence, prevalence
url http://www.reumatismo.org/index.php/reuma/article/view/562
work_keys_str_mv AT mgovoni epidemiologyofgoutandchondrocalcinosis
AT abortoluzzi epidemiologyofgoutandchondrocalcinosis
AT gciancio epidemiologyofgoutandchondrocalcinosis